Articular cartilage was predicted to be one of the first tissues to successfully be regenerated,
but this proved incorrect. In contrast, bone (but also vasculature and cardiac tissues) has …

Articular cartilage injury is a frequent worldwide disease, while effective treatment is urgently
needed. Due to lack of blood vessels and nerves, the ability of cartilage to self-repair is …

Today, the most frequent chronic musculoskeletal disorder and the leading cause of
disability in the elderly is osteoarthritis (OA). Approximately 43 million people in the United …

Osteochondral tissue engineering has shown an increasing development to provide suitable
strategies for the regeneration of damaged cartilage and underlying subchondral bone …

Introduction Identification of a suitable treatment for osteochondral repair presents a major
challenge due to existing limitations and an urgent clinical need remains for an off-the-shelf …

Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

Multi-material 3D printing technologies that resolve features at different lengths down to the
microscale open new avenues for regenerative medicine, particularly in the engineering of …

The osteochondral tissue is an interface between two distinct tissues: articular cartilage and
bone. These two tissues are significantly diverse with regard to their chemical compositions …

Background: Chondral lesions in athletically active patients cause considerable morbidity,
and treatment with existing cell-based therapies can be challenging. Bone marrow has been …

Objective: The purpose of our study was to determine the effectiveness of cartilage repair
utilizing 1-step surgery with bone marrow aspirate concentrate (BMAC) and a collagen I/III …