COVID-19 annual update: a narrative review
M Biancolella, VL Colona, L Luzzatto, JL Watt… - Human genomics, 2023 - Springer
Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …
A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes
Genome-wide association studies (GWASs) have identified more than 200 genomic loci for
breast cancer risk, but specific causal genes in most of these loci have not been identified. In …
breast cancer risk, but specific causal genes in most of these loci have not been identified. In …
A proteome-wide association study identifies putative causal proteins for breast cancer risk
Background Genome-wide association studies (GWAS) have identified more than 200
breast cancer risk-associated genetic loci, yet the causal genes and biological mechanisms …
breast cancer risk-associated genetic loci, yet the causal genes and biological mechanisms …
A multi-tissue, splicing-based joint transcriptome-wide association study identifies susceptibility genes for breast cancer
Splicing-based transcriptome-wide association studies (splicing-TWASs) of breast cancer
have the potential to identify susceptibility genes. However, existing splicing-TWASs test the …
have the potential to identify susceptibility genes. However, existing splicing-TWASs test the …
Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions
Genome-wide association studies have identified approximately 200 genetic risk loci for
breast cancer, but the causal variants and target genes are mostly unknown. We sought to …
breast cancer, but the causal variants and target genes are mostly unknown. We sought to …
Identification of target proteins for breast cancer genetic risk loci and blood risk biomarkers in a large study by integrating genomic and proteomic data
Genome‐wide association studies (GWAS) have identified around 200 loci associated with
breast cancer risk. However, protein targets for these loci remain largely unknown …
breast cancer risk. However, protein targets for these loci remain largely unknown …
Integrating muti-omics data to identify tissue-specific DNA methylation biomarkers for cancer risk
The relationship between tissue-specific DNA methylation and cancer risk remains
inadequately elucidated. Leveraging resources from the Genotype-Tissue Expression …
inadequately elucidated. Leveraging resources from the Genotype-Tissue Expression …
[HTML][HTML] Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes
African-ancestry (AA) participants are underrepresented in genetics research. Here, we
conducted a transcriptome-wide association study (TWAS) in AA female participants to …
conducted a transcriptome-wide association study (TWAS) in AA female participants to …
Expression-and splicing-based multi-tissue transcriptome-wide association studies identified multiple genes for breast cancer by estrogen-receptor status
Background Although several transcriptome-wide association studies (TWASs) have been
performed to identify genes associated with overall breast cancer (BC) risk, only a few TWAS …
performed to identify genes associated with overall breast cancer (BC) risk, only a few TWAS …