Extracellular matrix-derived biomaterials in engineering cell function

H Xing, H Lee, L Luo, TR Kyriakides - Biotechnology advances, 2020 - Elsevier
Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

Applications of decellularized materials in tissue engineering: advantages, drawbacks and current improvements, and future perspectives

J Liao, B Xu, R Zhang, Y Fan, H Xie, X Li - Journal of Materials …, 2020 - pubs.rsc.org
Decellularized materials (DMs) are attracting more and more attention because of their
native structures, comparatively high bioactivity, low immunogenicity and good …

Inorganic polyphosphates as storage for and generator of metabolic energy in the extracellular matrix

WEG Müller, HC Schröder, X Wang - Chemical reviews, 2019 - ACS Publications
Inorganic polyphosphates (polyP) consist of linear chains of orthophosphate residues,
linked by high-energy phosphoanhydride bonds. They are evolutionarily old biopolymers …

Solubilized extracellular matrix bioscaffolds derived from diverse source tissues differentially influence macrophage phenotype

JL Dziki, DS Wang, C Pineda, BM Sicari… - … research Part A, 2017 - Wiley Online Library
The host response to biomaterials is a critical determinant of their success or failure in tissue‐
repair applications. Macrophages are among the first responders in the host response to …

The host response to naturally-derived extracellular matrix biomaterials

AH Morris, DK Stamer, TR Kyriakides - Seminars in immunology, 2017 - Elsevier
Biomaterials based on natural materials including decellularized tissues and tissue-derived
hydrogels are becoming more widely used for clinical applications. Because of their native …

Macrophage phenotype in response to ECM bioscaffolds

L Huleihel, JL Dziki, JG Bartolacci, T Rausch… - Seminars in …, 2017 - Elsevier
Macrophage presence and phenotype are critical determinants of the healing response
following injury. Downregulation of the pro-inflammatory macrophage phenotype has been …

Porcine lung-derived extracellular matrix hydrogel properties are dependent on pepsin digestion time

RA Pouliot, BM Young, PA Link, HE Park… - … Engineering Part C …, 2020 - liebertpub.com
Hydrogels derived from decellularized lungs are promising materials for tissue engineering
in the development of clinical therapies and for modeling the lung extracellular matrix (ECM) …

Injectable extracellular matrix hydrogels as scaffolds for spinal cord injury repair

D Tukmachev, S Forostyak, Z Koci… - … Engineering Part A, 2016 - liebertpub.com
Restoration of lost neuronal function after spinal cord injury (SCI) still remains a big
challenge for current medicine. One important repair strategy is bridging the SCI lesion with …

Extracellular matrix bioscaffolds as immunomodulatory biomaterials

JL Dziki, L Huleihel, ME Scarritt… - Tissue Engineering Part …, 2017 - liebertpub.com
Suppression of the recipient immune response is a common component of tissue and organ
transplantation strategies and has also been used as a method of mitigating the …

Host response to biomaterials for cartilage tissue engineering: key to remodeling

F Wei, S Liu, M Chen, G Tian, K Zha, Z Yang… - … in Bioengineering and …, 2021 - frontiersin.org
Biomaterials play a core role in cartilage repair and regeneration. The success or failure of
an implanted biomaterial is largely dependent on host response following implantation. Host …