The seed of Nigella sativa (N. sativa) has been used in different civilization around the world
for centuries to treat various animal and human ailments. So far, numerous studies …

Autophagy is an explicit cellular process to deliver dissimilar cytoplasmic misfolded proteins,
lipids and damaged organelles to the lysosomes for degradation and elimination. The …

Background. Diabetes mellitus is a chronic metabolic disorder characterized by persistent
hyperglycemia. It affects millions of people globally. In spite of many antidiabetic drugs that …

Metformin is a plant-based drug belonging to the class of biguanides and is known to treat
type-2 diabetes mellitus (T2DM). The drug, combined with controlling blood glucose levels …

Epilepsy is a chronic neurological disease characterized by recurrent seizures. Epilepsy is
observed as a well‐controlled disease by anti‐epileptic agents (AEAs) in about 69 …

Neuroinflammation and epilepsy are different pathologies, but, in some cases, they are so
closely related that the activation of one of the pathologies leads to the development of the …

To date, there is no cure or disease-modifying agents available for most well-known
neurological disorders. Current therapy is typically focused on relieving symptoms and …

Background Available anti-seizure medications (ASMs) target the symptomatology of the
disease rather than any significant disease/epileptogenesis modifying actions. There are …

Metformin is a drug in the family of biguanide compounds that is widely used in the treatment
of type 2 diabetes (T2D). Interestingly, the therapeutic potential of metformin expands its …

Metformin, a widely prescribed medication for type 2 diabetes, has garnered increasing
attention for its potential neuroprotective properties due to the growing demand for …