Indole is a significant nitrogen-based heterocycle with particular importance in the synthesis
of heterocyclic scaffolds. Indole based compounds have been recently attracting much …

Simultaneous deconstructive ring-opening and skeletal reconstruction of an inert, aromatic
pyridinium ring is of great importance in synthetic communities. However, research in this …

An unprecedented base-promoted multi-component one-pot dearomatization of N-alkyl
activated azaarenes was developed, which enabled the synthesis of complex and diverse …

Bridged rings are frequently encountered in natural products and biologically active
molecules, which have significant application in the field of medicinal chemistry, natural …

We report an unexpected dearomative periphery modification strategy for transforming
quinolinium salts into structurally crowded pyrrolidine–tetrahydroquinoline polycyclic …

A new organocatalytic double annulation cascade involving scission/recombination of NO
bonds of nitrones is reported for the first time, and used to produce a range of hitherto …

Reported herein is an unexpected construction of functionalized π-extended indolizine
polycycles through a one-pot two-step cascade process comprising the base-promoted …

The development of chiral ligands to fine-tune stereocontrol in asymmetric catalysis is of
great demand. To diversify the Py-2NO ligand library recently developed by our group …

AlCl3-mediated nucleophilic ring-opening reactions of indoline-2-thiones with various acyl
cyclopropanes, bi-cyclopropanes and spirocyclic cyclopropanes were investigated. A series …

Expanding the chemical space of chiral N-oxides and chiral 2, 2′-bipyridine ligands is in
great demand in asymmetric catalysis. Herein, a new class of C2-symmetric bipyridine …