Flavonoids: Overview of biosynthesis, biological activity, and current extraction techniques

S Liga, C Paul, F Péter - Plants, 2023 - mdpi.com
Recently, increased attention has been paid to natural sources as raw materials for the
development of new added-value products. Flavonoids are a large family of polyphenols …

[HTML][HTML] Mechanisms of ferroptosis regulating oxidative stress and energy metabolism in myocardial ischemia-reperfusion injury and a novel perspective of natural …

T Zhang, W Deng, Y Deng, Y Liu, S Xiao, Y Luo… - Biomedicine & …, 2023 - Elsevier
Acute myocardial infarction remains the leading cause of death in humans. Timely
restoration of blood perfusion to ischemic myocardium remains the most effective strategy in …

The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline

J Melrose - Antioxidants, 2023 - mdpi.com
Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …

An insight on ophthalmic drug delivery systems: focus on polymeric biomaterials-based carriers

M Shafiq, M Rafique, Y Cui, L Pan, CW Do… - Journal of Controlled …, 2023 - Elsevier
Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …

Flavonoids in treatment of chronic kidney disease

YL Cao, JH Lin, HP Hammes, C Zhang - Molecules, 2022 - mdpi.com
Chronic kidney disease (CKD) is a progressive systemic disease, which changes the
function and structure of the kidneys irreversibly over months or years. The final common …

Research progress in the molecular mechanism of ferroptosis in Parkinson's disease and regulation by natural plant products

K Yang, L Zeng, J Zeng, Y Deng, S Wang, H Xu… - Ageing Research …, 2023 - Elsevier
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder of the
central nervous system after Alzheimer's disease. The current understanding of PD focuses …

Baicalein as promising anticancer agent: A comprehensive analysis on molecular mechanisms and therapeutic perspectives

AKMH Morshed, S Paul, A Hossain, T Basak… - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a multifactorial disease characterized by excessive cell
proliferation in a specific organ. The most common treatments include chemotherapy …

Review of bioactivity and structure-activity relationship on baicalein (5, 6, 7-trihydroxyflavone) and wogonin (5, 7-dihydroxy-8-methoxyflavone) derivatives: Structural …

Z Zhao, M Nian, H Qiao, X Yang, S Wu… - European Journal of …, 2022 - Elsevier
Abstract Baicalein (5, 6, 7-trihydroxyflavone) and wogonin (5, 7-dihydroxy-8-
methoxyflavone), as typical flavonoids isolated from Scutellaria baicalensis, are well …

[HTML][HTML] Identification of bioactive compounds and potential mechanisms of scutellariae radix-coptidis rhizoma in the treatment of atherosclerosis by integrating …

L Ji, T Song, C Ge, Q Wu, L Ma, X Chen, T Chen… - Biomedicine & …, 2023 - Elsevier
Objective This study aims at investigating the potential targets and functional mechanisms of
Scutellariae Radix-Coptidis Rhizoma (QLYD) against atherosclerosis (AS) through network …

Understanding mechanistic aspect of the therapeutic role of herbal agents on neuroplasticity in cerebral ischemic-reperfusion injury

A Bangar, H Khan, A Kaur, K Dua, TG Singh - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Stroke is one of the leading causes of death and disability.
The only FDA-approved therapy for treating stroke is tissue plasminogen activator (tPA) …