Cardiac structure remodeling and dysfunction are common complications of diabetes, often
leading to serious cardiovascular events. MOTS-c, a mitochondria-derived peptide …

Heart failure with preserved ejection fraction (HFpEF) afflicts over half of all patients with
heart failure and is a debilitating and fatal syndrome affecting postmenopausal women more …

Background Heart failure with preserved ejection fraction (HFpEF) represents a syndrome
involving multiple pathophysiologic disorders and clinical phenotypes. This complexity …

Aim To uncover sex-related microvascular abnormalities that underlie the early presentation
of reduced perfusion in leg skeletal muscle in a type II rat model of diabetic cardiomyopathy …

Microvascular dysfunction (mvD) has been implicated as the primary hallmark of several
cardiac and inflammatory diseases (eg, diabetes, heart failure), affecting millions of people …

People with diabetes mellitus (DM) are at an increased risk for myocardial infarction (MI)
than age matched people without DM. However, assays for pre-clinical therapy are …