Genetics of the phenotypic evolution in sheep: a molecular look at diversity-driving genes

P Kalds, S Zhou, Y Gao, B Cai, S Huang… - Genetics Selection …, 2022 - Springer
Background After domestication, the evolution of phenotypically-varied sheep breeds has
generated rich biodiversity. This wide phenotypic variation arises as a result of hidden …

Life in deserts: The genetic basis of mammalian desert adaptation

JL Rocha, R Godinho, JC Brito, R Nielsen - Trends in Ecology & Evolution, 2021 - cell.com
Deserts are among the harshest environments on Earth. The multiple ages of different
deserts and their global distribution provide a unique opportunity to study repeated …

Whole-body adipose tissue multi-omic analyses in sheep reveal molecular mechanisms underlying local adaptation to extreme environments

YX Xu, B Wang, JN Jing, R Ma, YH Luo, X Li… - Communications …, 2023 - nature.com
The fat tail of sheep is an important organ that has evolved to adapt to extreme
environments. However, the genetic mechanisms underlying the fat tail phenotype remain …

RNA-Seq based genetic variant discovery provides new insights into controlling fat deposition in the tail of sheep

MR Bakhtiarizadeh, AA Alamouti - Scientific Reports, 2020 - nature.com
Genetic basis of fat deposition in sheep tail have not been completely elucidated yet.
Understanding the genetic mechanisms controlling fat-tail size can improve breeding …

Trends towards revealing the genetic architecture of sheep tail patterning: Promising genes and investigatory pathways

P Kalds, Q Luo, K Sun, S Zhou, Y Chen… - Animal …, 2021 - Wiley Online Library
Different sheep breeds have evolved after initial domestication, generating various tail
phenotypic patterns. The phenotypic diversity of sheep tail patterns offers ideal materials for …

Estimates of genomic inbreeding and identification of candidate regions that differ between Chinese indigenous sheep breeds

J Liu, L Shi, Y Li, L Chen, D Garrick, L Wang… - Journal of Animal …, 2021 - Springer
Background A run of homozygosity (ROH) is a consecutive tract of homozygous genotypes
in an individual that indicates it has inherited the same ancestral haplotype from both …

Integrative analysis of Iso-Seq and RNA-seq data reveals transcriptome complexity and differentially expressed transcripts in sheep tail fat

Z Yuan, L Ge, J Sun, W Zhang, S Wang, X Cao, W Sun - PeerJ, 2021 - peerj.com
Background Nowadays, both customers and producers prefer thin-tailed fat sheep. To
effectively breed for this phenotype, it is important to identify candidate genes and uncover …

Identifying loci under positive selection in complex population histories

A Refoyo-Martínez, RR da Fonseca… - Genome …, 2019 - genome.cshlp.org
Detailed modeling of a species' history is of prime importance for understanding how natural
selection operates over time. Most methods designed to detect positive selection along …

[HTML][HTML] Natural adaptation and human selection of northeast African sheep genomes

AM Ahbara, HH Musa, C Robert, A Abebe… - Genomics, 2022 - Elsevier
African sheep manifest diverse but distinct physio-anatomical traits, which are the outcomes
of natural-and human-driven selection. Here, we generated 34.8 million variants from 150 …

Novel and known signals of selection for fat deposition in domestic sheep breeds from Africa and Eurasia

S Mastrangelo, H Bahbahani, B Moioli, A Ahbara… - PLoS …, 2019 - journals.plos.org
Genomic regions subjected to selection frequently show signatures such as within-
population reduced nucleotide diversity and outlier values of differentiation among …