Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia

E Connell, G Le Gall, MG Pontifex, S Sami… - Molecular …, 2022 - Springer
A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

[HTML][HTML] Effects of psychological, environmental and physical stressors on the gut microbiota

JP Karl, AM Hatch, SM Arcidiacono… - Frontiers in …, 2018 - frontiersin.org
Stress, a ubiquitous part of daily human life, has varied biological effects which are
increasingly recognized as including modulation of commensal microorganisms residing in …

Probiotic Bifidobacterium strains and galactooligosaccharides improve intestinal barrier function in obese adults but show no synergism when used together as …

JA Krumbeck, HE Rasmussen, RW Hutkins, J Clarke… - Microbiome, 2018 - Springer
Background One way to improve both the ecological performance and functionality of
probiotic bacteria is by combining them with a prebiotic in the form of a synbiotic. However …

Changes in intestinal microbiota composition and metabolism coincide with increased intestinal permeability in young adults under prolonged physiological stress

JP Karl, LM Margolis, EH Madslien… - American Journal …, 2017 - journals.physiology.org
The magnitude, temporal dynamics, and physiological effects of intestinal microbiome
responses to physiological stress are poorly characterized. This study used a systems …

High-throughput screen identifies host and microbiota regulators of intestinal barrier function

I Grosheva, D Zheng, M Levy, O Polansky… - Gastroenterology, 2020 - Elsevier
Background & Aims The intestinal barrier protects intestinal cells from microbes and
antigens in the lumen—breaches can alter the composition of the intestinal microbiota, the …

Alterations in fecal short-chain fatty acids in patients with irritable bowel syndrome: A systematic review and meta-analysis

Q Sun, Q Jia, L Song, L Duan - Medicine, 2019 - journals.lww.com
Background: Recent studies indicate that gut microbiota disorders potentially contribute to
the pathogenesis of irritable bowel syndrome (IBS), which can be partly reflected by fecal …

Bioaccessibility and bioactivity of cereal polyphenols: A review

B Ed Nignpense, N Francis, C Blanchard… - Foods, 2021 - mdpi.com
Cereal bioactive compounds, especially polyphenols, are known to possess a wide range of
disease preventive properties that are attributed to their antioxidant and anti-inflammatory …

Association between blood microbiome and type 2 diabetes mellitus: A nested case‐control study

J Qiu, H Zhou, Y Jing, C Dong - Journal of clinical laboratory …, 2019 - Wiley Online Library
Background Although recent studies have indicated that gut microbiome dysbiosis was
significantly associated with the onset of type 2 diabetes mellitus (T2DM), information on the …

Nickel exposure induces gut microbiome disorder and serum uric acid elevation

J Yang, P Feng, Z Ling, A Khan, X Wang, Y Chen… - Environmental …, 2023 - Elsevier
Serum uric acid elevation has been found in long-term nickel (Ni) exposure occupational
workers, but the mechanism is unclear. In this study, the relationship between Ni exposure …

Beneficial Effects of Potentilla discolor Bunge Water Extract on Inflammatory Cytokines Release and Gut Microbiota in High-Fat Diet and Streptozotocin-Induced Type …

L Han, T Li, M Du, R Chang, B Zhan, X Mao - Nutrients, 2019 - mdpi.com
Potentilla discolor Bunge (PDB), a perennial herb, has been used as a traditional Chinese
medicine in the therapy of many diseases. The aim of the current study was to investigate …