Carcinogenic polycyclic aromatic hydrocarbon‐DNA adducts and mechanism of action

WM Baird, LA Hooven… - Environmental and …, 2005 - Wiley Online Library
Polycyclic aromatic hydrocarbons (PAHs) are a class of widespread environmental
carcinogens. Most of our knowledge of their mechanisms of metabolic activation to DNA …

Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of the In Vivo and In Vitro Studies

A Nemmar, JA Holme, I Rosas… - BioMed research …, 2013 - Wiley Online Library
Epidemiological and clinical studies have linked exposure to particulate matter (PM) to
adverse health effects, which may be registered as increased mortality and morbidity from …

Bioavailability and risk assessment of orally ingested polycyclic aromatic hydrocarbons

A Ramesh, SA Walker, DB Hood… - … journal of toxicology, 2004 - journals.sagepub.com
Polycyclic aromatic hydrocarbons (PAHs) are a family of toxicants that are ubiquitous in the
environment. These contaminants generate considerable interest, because some of them …

Polycyclic aromatic hydrocarbons and digestive tract cancers: a perspective

DL Diggs, AC Huderson, KL Harris… - … science and health …, 2011 - Taylor & Francis
Cancers of the colon are most common in the Western world. In majority of these cases,
there is no familial history and sporadic gene damage seems to play an important role in the …

Aryl hydrocarbon receptor–independent toxicity of weathered crude oil during fish development

JP Incardona, MG Carls, H Teraoka… - Environmental …, 2005 - ehp.niehs.nih.gov
Polycyclic aromatic hydrocarbons (PAHs), derived largely from fossil fuels and their
combustion, are pervasive contaminants in rivers, lakes, and nearshore marine habitats …

[HTML][HTML] Lung cancer associated with combustion particles and fine particulate matter (PM2. 5)-The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl …

JA Holme, J Vondráček, M Machala… - Biochemical …, 2023 - Elsevier
Air pollution is the leading cause of lung cancer after tobacco smoking, contributing to 20%
of all lung cancer deaths. Increased risk associated with living near trafficked roads …

A review of PAH exposure from the combustion of biomass fuel and their less surveyed effect on the blood parameters

A Kamal, A Cincinelli, T Martellini, RN Malik - Environmental science and …, 2015 - Springer
Many epidemiological studies from all over the world have reported that populations of rural
and urban environments differ in their health issues due to the differences in the countrywide …

Environmental xenobiotics and nuclear receptors—Interactions, effects and in vitro assessment

J Janošek, K Hilscherová, L Bláha, I Holoubek - Toxicology in vitro, 2006 - Elsevier
A group of intracellular nuclear receptors is a protein superfamily including arylhydrocarbon
AhR, estrogen ER, androgen AR, thyroid TR and retinoid receptors RAR/RXR as well as …

In vitro profiling of toxic effects of environmental polycyclic aromatic hydrocarbons on nuclear receptor signaling, disruption of endogenous metabolism and induction …

P Šimečková, K Pěnčíková, O Kováč, J Slavík… - Science of The Total …, 2022 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) may interact with multiple intracellular receptors
and related signaling pathways. We comprehensively evaluated the toxicity profiles of six …

[HTML][HTML] Polycyclic aromatic hydrocarbons

H Choi, R Harrison, H Komulainen… - WHO guidelines for …, 2010 - ncbi.nlm.nih.gov
The term polycyclic organic matter (POM) defines a broad class of compounds that generally
includes all organic structures containing three or more fused aromatic rings. These …