[PDF][PDF] Diagnosis, management, and treatment of hepatitis C

DB Strader, T Wright, DL Thomas, LB Seeff - Hepatology, 2004 - Wiley Online Library
Background The hepatitis C virus (HCV) is a major public health problem and a leading
cause of chronic liver disease. In the United States, the Centers for Disease Control and …

Hepatitis C: the clinical spectrum of disease

JH Hoofnagle - Hepatology, 1997 - journals.lww.com
Hepatitis C virus (HCV) accounts for approximately 20% of cases of acute hepatitis, 70% of
chronic hepatitis, and 30% of end-stage liver disease in the United States. The acute …

Updated definitions of healthy ranges for serum alanine aminotransferase levels

D Prati, E Taioli, A Zanella, ED Torre… - Annals of internal …, 2002 - acpjournals.org
Background: Serum alanine aminotransferase (ALT) activity, the variable most commonly
measured to assess hepatic disease, fails to identify many patients with hepatic injury …

[PDF][PDF] Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values

P Mofrad, MJ Contos, M Haque, C Sargeant… - …, 2003 - Wiley Online Library
A retrospective study was performed to (1) characterize the clinical and histologic features of
those with nonalcoholic fatty liver disease (NAFLD) and normal alanine aminotransferase …

AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection

SG Sheth, SL Flamm, FD Gordon… - Official journal of the …, 1998 - journals.lww.com
Objective: A liver biopsy is necessary to grade and stage chronic hepatitis C virus (HCV)
infection. In a previous study of patients with nonalcoholic liver disease, an aspartate …

Guidelines on the use of liver biopsy in clinical practice

A Grant, J Neuberger - Gut, 1999 - gut.bmj.com
Erlich is credited with the first liver aspiration in 1883 and subsequently the first
percutaneous liver biopsy for diagnostic purposes was reported in 1923. 1 The technique …

The treatment of chronic viral hepatitis

JH Hoofnagle, AM Di Bisceglie - New England Journal of …, 1997 - Mass Medical Soc
Chronic viral hepatitis is the principal cause of chronic liver disease, cirrhosis, and
hepatocellular carcinoma in the world and now ranks as the chief reason for liver …

Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease

W Goessling, JM Massaro, RS Vasan… - Gastroenterology, 2008 - Elsevier
BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) is the hepatic
manifestation of obesity and metabolic syndrome (MetS). Alanine aminotransferase (ALT) …

[HTML][HTML] Viral hepatitis: Milestones, unresolved issues, and future goals

P Torre, A Aglitti, M Masarone… - World journal of …, 2021 - ncbi.nlm.nih.gov
In this review the current overall knowledge on hepatitis A, B, C, D, and E will be discussed.
These diseases are all characterized by liver inflammation but have significant differences in …

Hepatitis C virus genotypes: an investigation of type-specific differences in geographic origin and disease

G Dusheiko, H Schmilovitz-Weiss, D Brown… - Hepatology, 1994 - journals.lww.com
Because of the nucleotide sequence diversity of different isolates of hepatitis C virus, it has
become important to clarify whether distinct genotypes of hepatitis C virus vary with respect …