Multiple sclerosis (MS) is a chronic, progressive disease of the central nervous system that is
characterised by inflammatory damage to the myelin sheath. Though often neglected …

Abstract From the Section Editor: The next two installments in the JNO “Disease of the Year:
Multiple Sclerosis” series focus on lessons that can be learned form the afferent visual …

There are adaptive T-cell and antibody autoimmune responses to myelin-derived peptides
in multiple sclerosis (MS) and to aquaporin-4 (AQP4) in neuromyelitis optica spectrum …

Objective To compare axonal loss in ganglion cells detected with swept-source optical
coherence tomography (SS-OCT) in eyes of patients with multiple sclerosis (MS) versus …

Multiple Sclerosis (MS) is an autoimmune disease driving inflammatory and degenerative
processes that damage the central nervous system (CNS). However, it is not well …

Understanding of the role of focal inflammation, a treatable feature, on neuro-axonal injury,
is paramount to optimize neuroprotective strategy in MS. To quantify the impact of focal …

Multiple Sclerosis (MS) results in color vision impairment regardless of optic neuritis (ON).
The exact location of injury remains undefined. The objective of this study is to identify the …

The relationship between brain diffusion microstructural changes and disability in multiple
sclerosis (MS) remains poorly understood. We aimed to explore the predictive value of …

Importance Before using brain volume loss (BVL) as a marker of therapeutic response in
multiple sclerosis (MS), certain biological and methodological issues must be clarified …

Background: Although patients with acute optic neuritis (ON) recover high-contrast visual
acuity (HCVA) to 20/40 or better in 95% of affected eyes, patients with a history of ON …