The role of amino acids in neurotransmission and fluorescent tools for their detection

R Dalangin, A Kim, RE Campbell - International journal of molecular …, 2020 - mdpi.com
Neurotransmission between neurons, which can occur over the span of a few milliseconds,
relies on the controlled release of small molecule neurotransmitters, many of which are …

d-amino Acids in Health and Disease: A Focus on Cancer

JJAJ Bastings, HM van Eijk, SW Olde Damink… - Nutrients, 2019 - mdpi.com
d-amino acids, the enantiomeric counterparts of l-amino acids, were long considered to be
non-functional or not even present in living organisms. Nowadays, d-amino acids are …

Age-associated changes in cumulus cells and follicular fluid: the local oocyte microenvironment as a determinant of gamete quality

E Babayev, FE Duncan - Biology of reproduction, 2022 - academic.oup.com
The ovary is the first organ to age in humans with functional decline evident already in
women in their early 30s. Reproductive aging is characterized by a decrease in oocyte …

D-Aspartic acid: an endogenous amino acid with an important neuroendocrine role

A D'Aniello - Brain research reviews, 2007 - Elsevier
d-Aspartic acid (d-Asp), an endogenous amino acid present in vertebrates and
invertebrates, plays an important role in the neuroendocrine system, as well as in the …

The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats

E Topo, A Soricelli, A D'Aniello, S Ronsini… - Reproductive Biology …, 2009 - Springer
Background D-aspartic acid is an amino acid present in neuroendocrine tissues of
invertebrates and vertebrates, including rats and humans. Here we investigated the effect of …

Glutamate signaling in peripheral tissues

E Hinoi, T Takarada, T Ueshima… - European Journal of …, 2004 - Wiley Online Library
The hypothesis that l‐glutamate (Glu) is an excitatory amino acid neurotransmitter in the
mammalian central nervous system is now gaining more support after the successful cloning …

D-Amino acids in mammals and their diagnostic value

K Hamase, A Morikawa, K Zaitsu - Journal of chromatography B, 2002 - Elsevier
Substantial amounts of d-amino acids are present in mammalian tissues; their function,
origin and relationship between pathophysiological processes have been of great interest …

Anti-inflammatory and neuroprotective agents in clinical trials for CNS disease and injury: where do we go from here?

K Mallah, C Couch, DM Borucki, A Toutonji… - Frontiers in …, 2020 - frontiersin.org
Neurological disorders are major contributors to death and disability worldwide. The
pathology of injuries and disease processes includes a cascade of events that often involve …

d‐Amino acids in biological systems

S Du, M Wey, DW Armstrong - Chirality, 2023 - Wiley Online Library
Investigations on the occurrence and biochemical roles of free D‐amino acids and D‐amino
acid‐containing peptides and proteins in living systems have increased in frequency and …

D-amino acids in the central nervous system in health and disease

SA Fuchs, R Berger, LWJ Klomp… - Molecular genetics and …, 2005 - Elsevier
Recent evidence has shown that d-amino acids are present in animals and humans in high
concentrations and fulfill specific biological functions. In the central nervous system, two d …