Aflatoxins: History, significant milestones, recent data on their toxicity and ways to mitigation

D Pickova, V Ostry, J Toman, F Malir - Toxins, 2021 - mdpi.com
In the early 1960s the discovery of aflatoxins began when a total of 100,000 turkey poults
died by hitherto unknown turkey “X” disease in England. The disease was associated with …

Caffeic acid protects against DNA damage, oxidative and inflammatory mediated toxicities, and upregulated caspases activation in the hepatorenal system of rats …

SE Owumi, CE Irozuru, UO Arunsi, AK Oyelere - Toxicon, 2022 - Elsevier
Aflatoxicosis can induce largescale toxicities in predisposed populations. Food fortification
with adequate antioxidant sources may reduce the toxic burden from aflatoxicosis. We …

Origanum vulgare Essential Oil Modulates the AFB1-Induced Oxidative Damages, Nephropathy, and Altered Inflammatory Responses in Growing Rabbits

MA Hassan, AMA Abo-Elmaaty, AW Zaglool… - Toxins, 2023 - mdpi.com
The current study was performed to investigate the toxic effects of aflatoxin B1 (AFB1)
through the evaluation of kidney function tests and histopathological examination of renal …

AFB1 Toxicity in Human Food and Animal Feed Consumption: A Review of Experimental Treatments and Preventive Measures

A Pożarska, K Karpiesiuk, W Kozera, U Czarnik… - International Journal of …, 2024 - mdpi.com
Aims: The current review aims to outline and summarize the latest research on aflatoxin, with
research studies describing natural, herbal and chemical compound applications in animal …

AFG1-induced TNF-α-mediated inflammation enhances gastric epithelial cell injury via CYP2E1

X Wu, W Meng, C Duan, J Cao, Y Wei, X Cui… - Food and Chemical …, 2023 - Elsevier
Abstract Aflatoxin G 1 (AFG 1), a member of the aflatoxin family with cytotoxic and
carcinogenic properties, is one of the most common mycotoxins occurring in various …

Decrease in reproductive dysfunction using aflatoxin B1 exposure: a treatment with 3‐indolepropionic acid in albino Wistar rat

SE Owumi, MT Otunla, ES Najophe, AK Oyelere - Andrologia, 2022 - Wiley Online Library
We assessed the individual and combined consequence of 3‐indolepropionic acid on
aflatoxin B1‐induced reproductive toxicity in rats. The experimental cohorts were dosed for …

[HTML][HTML] Nigella sativa oil protects against cadmium-induced intestinal toxicity via promotion of anti-inflammatory mechanisms, mucin expression and microbiota …

AS Akinrinde, AO Adekanmbi… - Avicenna journal of …, 2022 - ncbi.nlm.nih.gov
Objective: This study examined the protective effects of Nigella sativa oil (NSO) on cadmium
(Cd)-induced alterations affecting gut morphology and microbiota composition, as well as …

Aflatoxins in food: Prevalence, health effects, and emerging trends in its mitigation—An updated review

B Balan, AS Dhaulaniya, M Kumar… - Food Safety and …, 2024 - Wiley Online Library
Mycotoxins are secondary metabolites produced by a variety of fungal and mold species.
One of the mycotoxin families that is often regarded as the most concerned one in human …

The Hydrophobic Extract of Sorghum bicolor (L. Moench) Enriched in Apigenin-Protected Rats against Aflatoxin B1-Associated Hepatorenal Derangement

SE Owumi, B Ajakaiye, AO Akinwunmi, SO Nwozo… - Molecules, 2023 - mdpi.com
Aflatoxin B1 (AFB1) is a recalcitrant metabolite produced by fungi species, and due to its
intoxications in animals and humans, it has been classified as a Group 1 carcinogen in …

Therapeutic applications of eucalyptus essential oils

RAE Shiekh, AM Atwa, AM Elgindy, AM Mustafa… - …, 2024 - Springer
Eucalyptus essential oils (EEOs) have gained significant attention recently anticipated to
their broad range of prospective benefits in various biological applications. They have been …