The local immune response is considered a key determinant in cervical carcinogenesis after
persistent infection with oncogenic, high‐risk human papillomavirus (HPV) infections …

Neoplastic growth was often regarded as an autonomous process driven by uncontrolled
expansion of malignant cell population. This view is now being transformed as it becomes …

Dengue fever and dengue hemorrhagic fever are mosquito-borne viral diseases. Dendritic
cell–specific ICAM-3 grabbing nonintegrin (DC-SIGN1, encoded by CD209), an attachment …

Caspases are important in the life and death of immune cells and therefore influence
immune surveillance of malignancies. We tested whether genetic variants in CASP8 …

Background: The functions of NF-κB in apoptosis and tumor development are controversial.
Results: Fas functions as a tumor suppressor, and NF-κB directly binds to multiple sites in …

Background: The FAS receptor–ligand system is a key regulator of apoptotic cell death, and
loss of FAS expression and gain of FAS ligand (FASL) expression play important roles in the …

Background: The FAS and FASL system plays a key role in regulating apoptotic cell death
and corruption of this signalling pathway has been shown to participate in immune escape …

Abstract Background The Mouse Genomes Project is an ongoing collaborative effort to
sequence the genomes of the common laboratory mouse strains. In 2011, the initial analysis …

Fas/Fas ligand (FasL) system is one of the key apoptotic signaling entities in the extrinsic
apoptotic pathway. De-regulation of this pathway, ie by mutations may prevent the immune …

The death receptor Fas and its physiological ligand (FasL) regulate apoptosis of cancerous
cells, thereby functioning as a critical component of the host cancer immunosurveillance …