Biomedical data, computational methods and tools for evaluating disease–disease associations

J Xiang, J Zhang, Y Zhao, FX Wu… - Briefings in …, 2022 - academic.oup.com
In recent decades, exploring potential relationships between diseases has been an active
research field. With the rapid accumulation of disease-related biomedical data, a lot of …

Maternal cognitive impairment associated with gestational diabetes mellitus—A review of potential contributing mechanisms

CM John, NIS Mohamed Yusof, SH Abdul Aziz… - International journal of …, 2018 - mdpi.com
Gestational diabetes mellitus (GDM) carries many risks, where high blood pressure,
preeclampsia and future type II diabetes are widely acknowledged, but less focus has been …

CaSSiDI: novel single-cell “Cluster Similarity Scoring and Distinction Index” reveals critical functions for PirB and context-dependent Cebpb repression

R Nechanitzky, P Ramachandran… - Cell Death & …, 2024 - nature.com
PirB is an inhibitory cell surface receptor particularly prominent on myeloid cells. PirB
curtails the phenotypes of activated macrophages during inflammation or tumorigenesis, but …

PCOSKBR2: a database of genes, diseases, pathways, and networks associated with polycystic ovary syndrome

M Sharma, RS Barai, I Kundu, S Bhaye, K Pokar… - Scientific reports, 2020 - nature.com
Abstract PolyCystic Ovary Syndrome KnowledgeBase (PCOSKBR2) is a manually curated
database with information on 533 genes, 145 SNPs, 29 miRNAs, 1,150 pathways, and 1,237 …

Effects of photodynamic therapy on Streptococcus mutans and enamel remineralization of multifunctional TiO2-HAP composite nanomaterials

R Wang, C Jia, N Zheng, S Liu, Z Qi, R Wang… - Photodiagnosis and …, 2023 - Elsevier
Background As photosensitizer and photocatalyst, titanium dioxide (TiO 2) can produce a
photodynamic reaction for antibacterial treatment. This study aims to explore a Titanium …

eRAM: encyclopedia of rare disease annotations for precision medicine

J Jia, Z An, Y Ming, Y Guo, W Li, Y Liang… - Nucleic acids …, 2018 - academic.oup.com
Rare diseases affect over a hundred million people worldwide, most of these patients are
not accurately diagnosed and effectively treated. The limited knowledge of rare diseases …

Classifying diseases by using biological features to identify potential nosological models

L Prieto Santamaría, EP García del Valle, M Zanin… - Scientific Reports, 2021 - nature.com
Established nosological models have provided physicians an adequate enough
classification of diseases so far. Such systems are important to correctly identify diseases …

PedAM: a database for pediatric disease annotation and medicine

J Jia, Z An, Y Ming, Y Guo, W Li, X Li… - Nucleic Acids …, 2018 - academic.oup.com
There is a significant number of children around the world suffering from the consequence of
the misdiagnosis and ineffective treatment for various diseases. To facilitate the precision …

VCF‐Server: A web‐based visualization tool for high‐throughput variant data mining and management

J Jiang, J Gu, T Zhao, H Lu - Molecular Genetics & Genomic …, 2019 - Wiley Online Library
Background Next‐generation sequencing (NGS) has been widely used in both clinics and
research. It has become the most powerful tool for diagnosing genetic disorders and …

[HTML][HTML] Construction of disease similarity networks using concept embedding and ontology

DH Wei, T Kang, HA Pincus, C Weng - Studies in health technology …, 2019 - ncbi.nlm.nih.gov
Discovering disease similarities are beneficial for the diagnosis and treatment of mental
diseases. In this research, we proposed a data driven method, that is, integrating a variety of …