A past history of pulmonary tuberculosis (TB) is a risk factor for long-term respiratory
impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high …

An estimated 58 million people have survived tuberculosis since 2000, yet many of them will
suffer from post-tuberculosis lung disease (PTLD). PTLD results from a complex interplay …

Background Accurate estimates of long-term mortality following tuberculosis treatment are
scarce. This systematic review and meta-analysis aimed to estimate the post-treatment …

Major epidemics, including some that qualify as pandemics, such as severe acute
respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A …

TB affects around 10.6 million people each year and there are now around 155 million TB
survivors. TB and its treatments can lead to permanently impaired health and wellbeing. In …

The absence of a gold standard to determine when antibiotics induce a sterilizing cure has
confounded the development of new approaches to treat pulmonary tuberculosis (PTB). We …

Background A substantial proportion of tuberculosis patients remain with pulmonary
symptoms and reduced physical capacity despite successful treatment. We performed a …

In small studies and cases series, a history of tuberculosis has been associated with both
airflow obstruction, which is characteristic of chronic obstructive pulmonary disease, and …

ABSTRACT COPD is a major global concern, increasingly so in the context of ageing
populations. The role of infections in disease pathogenesis and progression is known to be …

Mechanisms underlying variability in transmission of Mycobacterium tuberculosis strains
remain undefined. By characterizing high and low transmission strains of M. tuberculosis in …