Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal
feature of astrocytes is their complex and visually enchanting morphology, referred to as …

Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Despite the availabilty of imaging-based and mass-spectrometry-based methods for spatial
proteomics, a key challenge remains connecting images with single-cell-resolution protein …

Astrocytes are morphologically complex, ubiquitous cells that are viewed as a
homogeneous population tiling the entire central nervous system (CNS). However, this view …

Astrocytes are now emerging as key participants in many aspects of brain development,
function and disease. In particular, new evidence shows that astrocytes powerfully control …

Epidemiological studies demonstrate an association between breast cancer (BC) and
systemic dysregulation of glucose metabolism. However, how BC influences glucose …

The adult CNS contains an abundant population of oligodendrocyte precursor cells (NG2+
cells) that generate oligodendrocytes and repair myelin, but how these ubiquitous …

Astrocytes participate in all essential CNS functions, including blood flow regulation, energy
metabolism, ion and water homeostasis, immune defence, neurotransmission, and adult …

Defining the microanatomic differences between the human brain and that of other
mammals is key to understanding its unique computational power. Although much effort has …

Background Excitatory synapses in the CNS are highly dynamic structures that can show
activity-dependent remodeling and stabilization in response to learning and memory …