Site-selective C–H functionalization to access the arene backbone of indoles and quinolines

B Prabagar, Y Yang, Z Shi - Chemical Society Reviews, 2021 - pubs.rsc.org
The site-selective C–H bond functionalization of heteroarenes can eventually provide
chemists with great techniques for editing and building complex molecular scaffolds. During …

Recent advances in metal‐catalyzed functionalization of indoles

K Urbina, D Tresp, K Sipps… - Advanced Synthesis & …, 2021 - Wiley Online Library
Indole is one of the most important heterocycles in organic synthesis, natural products, and
drug discovery. Recently, tremendous advances in the selective functionalization of indoles …

Unactivated Alkyl Halides in Transition-Metal-Catalyzed C–H Bond Alkylation

SB Ankade, AB Shabade, V Soni, B Punji - ACS Catalysis, 2021 - ACS Publications
Alkylation represents an important organic transformation in molecular science to develop
privileged alkylated arenes and heteroarenes. Especially, the direct C–H bond alkylation …

Iron catalysts with N-ligands for carbene transfer of diazo reagents

C Damiano, P Sonzini, E Gallo - Chemical Society Reviews, 2020 - pubs.rsc.org
Transition-metal-catalyzed carbene transfer reactions, involving diazo compounds and their
precursors, are powerful tools for creating new C–C bonds. Depending on the involved …

Iron-catalyzed regioselective C–H alkylation of indoles: an additive-free approach in renewable solvent

C Pradhan, RA Jagtap, PP Samal, S Krishnamurty… - Green …, 2023 - pubs.rsc.org
Alkylated indoles are important motifs in various biologically active molecules and drug
candidates. Herein, we report a mild and efficient iron-catalyzed protocol for synthesizing …

Recent advances in pincer–nickel catalyzed reactions

V Arora, H Narjinari, PG Nandi, A Kumar - Dalton Transactions, 2021 - pubs.rsc.org
Organometallic catalysts have played a key role in accomplishing numerous synthetically
valuable organic transformations that are either otherwise not possible or inefficient. The use …

Progress and prospects in copper-catalyzed C–H functionalization

T Aneeja, M Neetha, CMA Afsina, G Anilkumar - RSC advances, 2020 - pubs.rsc.org
Copper-catalyzed C–H functionalization is becoming a significant area in organic chemistry.
Copper is now widely used as a catalyst in organic synthesis as it is inexpensive and not …

Recent Advances in Metal‐catalyzed Alkylation, Alkenylation and Alkynylation of Indole/indoline Benzenoid Nucleus

S Pradhan, PB De, TA Shah… - Chemistry–An Asian …, 2020 - Wiley Online Library
Selective editing of the benzenoid C− H bonds (C4− C7) in indoles/indolines has received
great interest because functionalized indoles/indolines are featured in many marketed drugs …

Advances in C(sp2)−H/C(sp2)−H Oxidative Coupling of (Hetero)arenes Using 3d Transition Metal Catalysts

S Bansal, AB Shabade, B Punji - Advanced Synthesis & …, 2021 - Wiley Online Library
Abstract C− H/C− H oxidative coupling has emerged as a straightforward and powerful
technique for the construction of (hetero) biaryls, with substantial application to drug …

Ligand-ligated Ni–Al bimetallic catalysis for C–H and C–C bond activation

YX Luan, M Ye - Chemical Communications, 2022 - pubs.rsc.org
Compared with non-ligated Ni–Al bimetallic catalysis, bifunctional ligand-ligated Ni–Al
bimetallic catalysis displays stronger synergism, not only affecting the electronic properties …