Succinate dehydrogenase (SDH)‐deficient neoplasia
AJ Gill - Histopathology, 2018 - Wiley Online Library
The succinate dehydrogenase (SDH) complex is a key respiratory enzyme composed of four
subunits: SDHA, SDHB, SDHC and SDHD. Remarkably, immunohistochemistry for SDHB …
subunits: SDHA, SDHB, SDHC and SDHD. Remarkably, immunohistochemistry for SDHB …
The 2022 revision of the World Health Organization classification of tumors of the urinary system and male genital organs: advances and challenges
SK Mohanty, A Lobo, L Cheng - Human pathology, 2023 - Elsevier
The fifth edition of the World Health Organization (WHO) classification of urinary and male
genital organ tumors has been recently published in 2022. The application of molecular …
genital organ tumors has been recently published in 2022. The application of molecular …
[HTML][HTML] New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia
K Trpkov, O Hes, SR Williamson, AJ Adeniran… - Modern Pathology, 2021 - Elsevier
Abstract The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
Fumarate hydratase–deficient renal cell carcinoma is strongly correlated with fumarate hydratase mutation and hereditary leiomyomatosis and renal cell carcinoma …
Hereditary leiomyomatosis and renal cell carcinoma syndrome–associated renal cell
carcinomas (RCC) are difficult to diagnose prospectively. We used immunohistochemistry …
carcinomas (RCC) are difficult to diagnose prospectively. We used immunohistochemistry …
Report from the international society of urological pathology (ISUP) consultation conference on molecular pathology of urogenital cancers: III: molecular pathology of …
Renal cell carcinoma (RCC) subtypes are increasingly being discerned via their molecular
underpinnings. Frequently this can be correlated to histologic and immunohistochemical …
underpinnings. Frequently this can be correlated to histologic and immunohistochemical …
A clinicopathologic and molecular analysis of fumarate hydratase-deficient renal cell carcinoma in 32 patients
HD Lau, E Chan, AC Fan, CA Kunder… - The American journal …, 2020 - journals.lww.com
Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare and recently
described entity associated with hereditary leiomyomatosis and RCC syndrome. FH …
described entity associated with hereditary leiomyomatosis and RCC syndrome. FH …
Tubulocystic carcinoma of the kidney with poorly differentiated foci: a frequent morphologic pattern of fumarate hydratase-deficient renal cell carcinoma
An emerging group of high-grade renal cell carcinomas (RCCs), particularly carcinomas
arising in the hereditary leiomyomatosis renal cell carcinoma syndrome (HLRCC), show …
arising in the hereditary leiomyomatosis renal cell carcinoma syndrome (HLRCC), show …
[HTML][HTML] Towards a new WHO classification of renal cell tumor: what the clinician needs to know—a narrative review
In 1952, renal cell carcinomas had been divided into 2 categories—clear cell or granular cell—
depending upon their cytoplasmic staining characteristics. In the following years, the …
depending upon their cytoplasmic staining characteristics. In the following years, the …
Characterization of MED12, HMGA2, and FH alterations reveals molecular variability in uterine smooth muscle tumors
N Mäkinen, K Kämpjärvi, N Frizzell, R Bützow… - Molecular cancer, 2017 - Springer
Uterine smooth muscle tumors range from benign leiomyomas to malignant
leiomyosarcomas. Based on numerous molecular studies, leiomyomas and …
leiomyosarcomas. Based on numerous molecular studies, leiomyomas and …
A distinctive, low‐grade oncocytic fumarate hydratase‐deficient renal cell carcinoma, morphologically reminiscent of succinate dehydrogenase‐deficient renal cell …
SC Smith, D Sirohi, C Ohe, JB McHugh… - …, 2017 - Wiley Online Library
Aims Fumarate hydratase (FH)‐deficient renal cell carcinoma (RCC) is a high‐grade,
aggressive tubulopapillary carcinoma, arising predominantly in the setting of the hereditary …
aggressive tubulopapillary carcinoma, arising predominantly in the setting of the hereditary …