Oxidative stress and oocyte cryopreservation: recent advances in mitigation strategies involving antioxidants

B Cao, J Qin, B Pan, IH Qazi, J Ye, Y Fang, G Zhou - Cells, 2022 - mdpi.com
Oocyte cryopreservation is widely used in assisted-reproductive technology and animal
production. However, cryopreservation not only induces a massive accumulation of reactive …

Vitrification of Mammalian Oocytes: Recent Studies on Mitochondrial Dysfunction

Y Zhu, H Liu, L Zheng, Y Luo, G Zhou, J Li… - Biopreservation and …, 2024 - liebertpub.com
Vitrification of reproductive cells is definitely essential and integral in animal breeding, as
well as in assisted reproduction. However, issues accompanied with this technology such as …

Glutathione Ethyl Ester Protects In Vitro-Maturing Bovine Oocytes against Oxidative Stress Induced by Subsequent Vitrification/Warming

T García-Martínez, M Vendrell-Flotats… - International journal of …, 2020 - mdpi.com
This study aimed to examine whether the addition of glutathione ethyl ester (GSH-OEt) to the
in vitro maturation (IVM) medium would improve the resilience of bovine oocytes to …

Resveratrol treatment increases mitochondrial biogenesis and improves viability of porcine germinal-vesicle stage vitrified-warmed oocytes

J Ito, K Shirasuna, T Kuwayama, H Iwata - Cryobiology, 2020 - Elsevier
Vitrification induces mitochondrial dysfunction in warmed oocytes, and degeneration and
biogenesis of mitochondria are crucial for maintaining oocyte quality. The present study …

Morphological, biochemical and functional studies to evaluate bovine oocyte vitrification

C Gutnisky, S Morado, T Gadze, A Donato, G Alvarez… - Theriogenology, 2020 - Elsevier
The aim of the present study was to evaluate the effect of vitrification on morphological,
biochemical and functional parameters of matured bovine oocytes at different recovery …

Effect of bovine oocyte vitrification with EGTA and post-warming recovery with resveratrol on meiotic spindle, mitochondrial function, reactive oxygen species, and …

E Gutierrez-Castillo, FA Diaz, SA Talbot, KR Bondioli - Theriogenology, 2023 - Elsevier
The present study aimed to determine the effects of the addition of EGTA to vitrification
solutions and a post-warming recovery period supplemented with 1 μM resveratrol on …

Resveratrol enhanced mitochondrial recovery from cryopreservation‐induced damages in oocytes and embryos

H Iwata - Reproductive Medicine and Biology, 2021 - Wiley Online Library
Background Mitochondria play a crucial role in nuclear maturation, fertilization, and
subsequent embryo development. Cryopreservation is an important assisted reproductive …

Resveratrol treatment during maturation enhances developmental competence of oocytes after prolonged ovary storage at 4 C in the domestic cat model

AR Piras, F Ariu, L Falchi, MT Zedda, S Pau… - Theriogenology, 2020 - Elsevier
Abstract Resveratrol (Resv; 3, 4, 5-trihydroxy-trans-stilbene) is a phytoalexin with antioxidant
activity that modulates redox homeostasis in oocytes and improves in vitro embryo …

Melatonin rescues the aneuploidy in mice vitrified oocytes by regulating mitochondrial heat product

L Gao, M Du, Q Zhuan, Y Luo, J Li, Y Hou, S Zeng… - Cryobiology, 2019 - Elsevier
Vitrification of germinal vesicle (GV) stage oocytes has been shown to be closely associated
with decreased rates of meiosis maturation and increased rates of aneuploidy. However …

Quality of vitrified porcine immature oocytes is improved by coculture with fresh oocytes during in vitro maturation

BY Jia, DC Xiang, B Zhang, GB Quan… - Molecular …, 2019 - Wiley Online Library
It is essential to enhance the in vitro maturation (IVM) condition for immature oocytes after
cryopreservation, particularly if limited numbers of oocytes collected from specific donors …