[HTML][HTML] Learnings from 30 years of reported efficacy and safety of vagus nerve stimulation (VNS) for epilepsy treatment: a critical review

DH Toffa, L Touma, T El Meskine, A Bouthillier… - Seizure, 2020 - Elsevier
Three decades after its introduction as an adjuvant therapeutic option in the management of
selective drug-resistant epilepsy cases (DRE), vagus nerve stimulation (VNS) retains …

The burden of epilepsy and unmet need in people with focal seizures

P Ioannou, DL Foster, JW Sander, S Dupont… - Brain and …, 2022 - Wiley Online Library
Background Epilepsy is one of the most common neurological conditions worldwide. As a
chronic condition, epilepsy imposes a significant burden on people with epilepsy and …

[图书][B] Epilepsy: a public health imperative

World Health Organization - 2019 - apps.who.int
Epilepsy is a brain disease characterized by abnormal electrical activity causing seizures or
unusual behaviour, sensations and sometimes loss of awareness. It carries neurological …

Psychiatric comorbidities in people with epilepsy

M Mula, AM Kanner, N Jetté… - Neurology: Clinical …, 2021 - AAN Enterprises
Purpose of Review To review the latest evidence concerning the epidemiology, clinical
implications, and management of psychiatric disorders in epilepsy. Recent Findings People …

[HTML][HTML] Systematic literature review of psychiatric comorbidities in adults with epilepsy

E Lu, N Pyatka, CJ Burant… - Journal of clinical …, 2021 - ncbi.nlm.nih.gov
Background and Purpose Mental illness is disproportionately common in people with
epilepsy (PWE). This systematic literature review identified original research articles that …

[HTML][HTML] ATP and adenosine—Two players in the control of seizures and epilepsy development

E Beamer, M Kuchukulla, D Boison, T Engel - Progress in neurobiology, 2021 - Elsevier
Despite continuous advances in understanding the underlying pathogenesis of
hyperexcitable networks and lowered seizure thresholds, the treatment of epilepsy remains …

Epilepsy and attention deficit hyperactivity disorder: connection, chance, and challenges

HC Fan, KL Chiang, KH Chang, CM Chen… - International Journal of …, 2023 - mdpi.com
Comorbidities are common in children with epilepsy, with nearly half of the patients having
at least one comorbidity. Attention deficit hyperactivity disorder (ADHD) is a psychiatric …

Neuropsychiatric and cognitive comorbidities in epilepsy

M Mula, H Coleman, SJ Wilson - CONTINUUM: Lifelong Learning …, 2022 - journals.lww.com
Neuropsychiatric and Cognitive Comorbidities in Epilepsy : CONTINUUM: Lifelong
Learning in Neurology Account Register Activate Subscription Help Subscribe American …

Impact of psychiatric comorbidities on the treatment of epilepsies in adults

M Mula - Expert Review of Neurotherapeutics, 2023 - Taylor & Francis
Introduction Epilepsy is often accompanied by psychiatric comorbidities and the
management of epilepsy in these patients presents unique challenges due to the interplay …

Beyond seizure control: treating comorbidities in epilepsy via targeting of the P2X7 receptor

B Gil, J Smith, Y Tang, P Illes, T Engel - International Journal of Molecular …, 2022 - mdpi.com
Epilepsy is one of the most common chronic diseases of the central nervous system (CNS).
Treatment of epilepsy remains, however, a clinical challenge with over 30% of patients not …