Shiga Toxin–Producing Escherichia coli and the Hemolytic–Uremic Syndrome | New England
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The severity of human infection by one of the many Shiga toxin-producing Escherichia coli
(STEC) is determined by a number of factors: the bacterial genome, the capacity of human …

First described by Gasser and colleagues 1 in 1955, hemolytic uremic syndrome (HUS) is
the clinical triad of thrombocytopenia, anemia, and acute kidney injury. It is classically …

Infections with Shiga toxin-producing Escherichia coli (STEC) cause outbreaks of severe
diarrheal disease in children and the elderly around the world. The severe complications …

Thrombotic microangiopathies (TMAs) are a heterogeneous group of syndromes presenting
with a distinct clinical triad: microangiopathic hemolytic anemia, thrombocytopenia, and …

Hemolytic uremic syndrome is commonly caused by Shiga toxin-producing Escherichia coli
(STEC). Up to 15% of individuals with STEC-associated hemorrhagic diarrhea develop …

Purpose of review: Thrombotic microangiopathy (TMA) is suspected in patients presenting
with thrombocytopenia and evidence of a microangiopathic hemolytic anemia. Patients with …

Objectives: Identify the etiology of illnesses caused by Escherichia coli. Review the
appropriate evaluation process for Escherichia coli infection. Outline the management …

Haemolytic uraemic syndrome (HUS) remains a leading cause of paediatric acute kidney
injury (AKI). Haemolytic uraemic syndrome is characterised by the triad of microangiopathic …

Thrombotic microangiopathy (TMA) refers to phenotypically similar disorders, including
hemolytic uremic syndromes (HUS) and thrombotic thrombocytopenic purpura (TTP). This …