Clinical application status of articular cartilage regeneration techniques: tissue‐engineered cartilage brings new hope

S Jiang, W Guo, G Tian, X Luo, L Peng… - Stem Cells …, 2020 - Wiley Online Library
Hyaline articular cartilage lacks blood vessels, lymphatics, and nerves and is characterised
by limited self‐repair ability following injury. Traditional techniques of articular cartilage …

Application and development of 3D bioprinting in cartilage tissue engineering

M Li, D Sun, J Zhang, Y Wang, Q Wei, Y Wang - Biomaterials Science, 2022 - pubs.rsc.org
Articular cartilage defects are one of the most common clinical diseases of bone articulation.
Early repair of damaged joint cartilage can effectively stop the progression of arthritis and …

[HTML][HTML] Synergistic chondrogenesis promotion and arthroscopic articular cartilage restoration via injectable dual-drug-loaded sulfated hyaluronic acid hydrogel for …

W Gao, K Chen, W He, S Zhao, D Cui, C Tao… - Composites Part B …, 2023 - Elsevier
Bone marrow stem cells (BMSCs)-loaded injectable hydrogels are promising vehicles for the
restoration of articular cartilage defect (ACD), while was limited with insufficient …

Biological strategies for osteoarthritis: from early diagnosis to treatment

AE Weber, IK Bolia, NA Trasolini - International orthopaedics, 2021 - Springer
Purpose To provide an updated review of the literature on the use of orthobiologics as a
potential treatment option to alleviate symptoms associated with osteoarthritis (OA), slow the …

[HTML][HTML] Exosomal miR-429 derived from adipose-derived stem cells ameliorated chondral injury in osteoarthritis via autophagy by targeting FEZ2

C Meng, Y Na, C Han, Y Ren, M Liu, P Ma… - International …, 2023 - Elsevier
Background Osteoarthritis (OA) is the most prevalent musculoskeletal disease, imposing a
significant public health burden. Exosomes might be an effective means of treating OA …

[HTML][HTML] Micro-and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis

Z Nabizadeh, M Nasrollahzadeh… - Beilstein Journal of …, 2022 - beilstein-journals.org
Osteoarthritis, which typically arises from aging, traumatic injury, or obesity, is the most
common form of arthritis, which usually leads to malfunction of the joints and requires …

Practical considerations for translating mesenchymal stromal cell-derived extracellular vesicles from bench to bed

PPY Lui, YT Leung - Pharmaceutics, 2022 - mdpi.com
Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) have shown
potential for the treatment of tendon and ligament injuries. This approach can eliminate the …

What is the optimal dose of adipose-derived mesenchymal stem cells treatment for knee osteoarthritis? A conventional and network meta-analysis of randomized …

Z Huang, S Zhang, M Cao, Z Lin, L Kong, X Wu… - Stem Cell Research & …, 2023 - Springer
Background Despite increasing clinical investigations underscoring the efficacy and safety
of adipose-derived mesenchymal stem cells (AD-MSCs) therapy in knee osteoarthritis …

Clinical efficacy of bone marrow aspirate concentrate versus stromal vascular fraction injection in patients with knee osteoarthritis: A systematic review and meta …

IK Bolia, S Bougioukli, WJ Hill… - … American journal of …, 2022 - journals.sagepub.com
Background: Knee injection using either bone marrow aspirate concentrate (BMAC) or
stromal vascular fraction (SVF) from adipose tissue has been shown to result in symptomatic …

Multifunctional hydrogels: advanced therapeutic tools for osteochondral regeneration

W Zhang, K Zha, W Hu, Y Xiong, S Knoedler… - Biomaterials …, 2023 - spj.science.org
Various joint pathologies such as osteochondritis dissecans, osteonecrosis, rheumatic
disease, and trauma, may result in severe damage of articular cartilage and other joint …