SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19

A Tsatsakis, D Calina, L Falzone, D Petrakis… - Food and Chemical …, 2020 - Elsevier
Common manifestations of COVID-19 are respiratory and can extend from mild symptoms to
severe acute respiratory distress. The severity of the illness can also extend from mild …

JAK-STAT pathway inhibition and their implications in COVID-19 therapy

S Satarker, AA Tom, RA Shaji, A Alosious… - Postgraduate …, 2021 - Taylor & Francis
As the incidence of COVID-19 increases with time, more and more efforts are made to pave
a way out for the therapeutic strategies to deal with the disease progression. Inflammation …

COVID-19, cytokines, inflammation, and spices: How are they related?

AB Kunnumakkara, V Rana, D Parama, K Banik… - Life sciences, 2021 - Elsevier
Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …

COVID-19 and vaccination: myths vs science

VP Chavda, Y Chen, J Dave, ZS Chen… - Expert Review of …, 2022 - Taylor & Francis
Introduction Several vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been developed since the inception of the coronavirus disease 2019 …

Rapid and sensitive SERS-based lateral flow test for SARS-CoV2-specific IgM/IgG antibodies

S Srivastav, A Dankov, M Adanalic… - Analytical …, 2021 - ACS Publications
As an immune response to COVID-19 infection, patients develop SARS-CoV-2-specific
IgM/IgG antibodies. Here, we compare the performance of a conventional lateral flow assay …

Identifying transcriptomic signatures and rules for SARS-CoV-2 infection

YH Zhang, H Li, T Zeng, L Chen, Z Li… - Frontiers in Cell and …, 2021 - frontiersin.org
The world-wide Coronavirus Disease 2019 (COVID-19) pandemic was triggered by the
widespread of a new strain of coronavirus named as severe acute respiratory syndrome …

[HTML][HTML] [Comment] COVID‑19 vaccine safety

RN Kostoff, MB Briggs, AL Porter… - International …, 2020 - spandidos-publications.com
In response to the SARS‑CoV‑2 outbreak, and the resulting COVID‑19 pandemic, a global
competition to develop an anti‑COVID‑19 vaccine has ensued. The targeted time frame for …

[HTML][HTML] Vaccine-and natural infection-induced mechanisms that could modulate vaccine safety

RN Kostoff, D Kanduc, AL Porter, Y Shoenfeld… - Toxicology reports, 2020 - Elsevier
A degraded/dysfunctional immune system appears to be the main determinant of
serious/fatal reaction to viral infection (for COVID-19, SARS, and influenza alike). There are …

Role of phytoconstituents in the management of COVID-19

A Das, D Pandita, GK Jain, P Agarwal… - Chemico-biological …, 2021 - Elsevier
Background COVID-19, a severe global pandemic caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has emerged as one of the most threatening …

Transcriptomic analysis of COVID‑19 lungs and bronchoalveolar lavage fluid samples reveals predominant B cell activation responses to infection

E Cavalli, MC Petralia, MS Basile… - International …, 2020 - spandidos-publications.com
The outbreak of the 2019 coronavirus disease (named, COVID‑19), caused by the novel
SARS‑CoV‑2 virus, represents a worldwide severe threat to public health. It is of the utmost …