Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19

C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in Molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …

Diagnostic, prognostic and mechanistic biomarkers of COVID-19 identified by mass spectrometric metabolomics

M Bourgin, S Durand, G Kroemer - Metabolites, 2023 - mdpi.com
A number of studies have assessed the impact of SARS-CoV-2 infection and COVID-19
severity on the metabolome of exhaled air, saliva, plasma, and urine to identify diagnostic …

Multi-omics reveals mechanisms of partial modulation of COVID-19 dysregulation by glucocorticoid treatment

M Spick, A Campbell, I Baricevic-Jones… - International journal of …, 2022 - mdpi.com
Treatments for COVID-19 infections have improved dramatically since the beginning of the
pandemic, and glucocorticoids have been a key tool in improving mortality rates. The UK's …

[HTML][HTML] Untargeted saliva metabolomics by liquid chromatography—Mass spectrometry reveals markers of COVID-19 severity

CF Frampas, K Longman, M Spick, HM Lewis… - PLoS …, 2022 - journals.plos.org
Background The COVID-19 pandemic is likely to represent an ongoing global health issue
given the potential for new variants, vaccine escape and the low likelihood of eliminating all …

Meta-analysis of COVID-19 metabolomics identifies variations in robustness of biomarkers

A Onoja, J Von Gerichten, HM Lewis, MJ Bailey… - International journal of …, 2023 - mdpi.com
The global COVID-19 pandemic resulted in widespread harms but also rapid advances in
vaccine development, diagnostic testing, and treatment. As the disease moves to endemic …

[HTML][HTML] Early Metabolomic and Immunologic Biomarkers as Prognostic Indicators for COVID-19

Z Chen, E Fung, CK Wong, L Ling, G Lui, CKC Lai… - Metabolites, 2024 - mdpi.com
This prospective study in Hong Kong aimed at identifying prognostic metabolomic and
immunologic biomarkers for Coronavirus Disease 2019 (COVID-19). We examined 327 …

Nucleotide, Phospholipid, and Kynurenine Metabolites Are Robustly Associated with COVID-19 Severity and Time of Plasma Sample Collection in a Prospective …

HAS Chatelaine, Y Chen, J Braisted, SH Chu… - International Journal of …, 2023 - mdpi.com
Understanding the molecular underpinnings of disease severity and progression in human
studies is necessary to develop metabolism-related preventative strategies for severe …

[HTML][HTML] Metabolomic Insights into COVID-19 Severity: A Scoping Review

E Pimentel, MM Banoei, J Kaur, CH Lee, BW Winston - Metabolites, 2024 - mdpi.com
Background: In 2019, SARS-CoV-2, the novel coronavirus, entered the world scene,
presenting a global health crisis with a broad spectrum of clinical manifestations …

Maintained imbalance of triglycerides, apolipoproteins, energy metabolites and cytokines in long-term COVID-19 syndrome patients

G Berezhnoy, R Bissinger, A Liu, C Cannet… - Frontiers in …, 2023 - frontiersin.org
Background Deep metabolomic, proteomic and immunologic phenotyping of patients
suffering from an infection with severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Targeted lipidomics data of COVID-19 patients

M Costanzo, M Caterino - Data in Brief, 2023 - Elsevier
The dataset provided with this article describes a targeted lipidomics analysis performed on
the serum of COVID-19 patients characterized by different degree of severity. As the ongoing …