[HTML][HTML] Bioavailability and health benefits of major isoflavone aglycones and their metabolites

YH Hsiao, CT Ho, MH Pan - Journal of Functional Foods, 2020 - Elsevier
Isoflavones are stored in various plants and widely present in different kinds of food in
variable amounts. However, isoflavone aglycones are found less frequently in natural …

Flavonoids in bone erosive diseases: perspectives in osteoporosis treatment

D Bellavia, E Dimarco, V Costa, V Carina… - Trends in Endocrinology …, 2021 - cell.com
Imbalance of bone homeostasis, with excessive bone resorption compared with bone
formation, leads to the development of progressive osteopenia leading to lower bone …

[HTML][HTML] Plant constituents and thyroid: A revision of the main phytochemicals that interfere with thyroid function

G Di Dalmazi, C Giuliani - Food and Chemical Toxicology, 2021 - Elsevier
In the past few decades, there has been a lot of interest in plant constituents for their
antioxidant, anti-inflammatory, anti-microbial and anti-proliferative properties. However …

The protective activity of genistein against bone and cartilage diseases

Z Wu, L Liu - Frontiers in Pharmacology, 2022 - frontiersin.org
Genistein, a natural isoflavone rich in soybean and leguminous plants, has been shown
various biological effects, such as anti-inflammation, anti-oxidation, anti-cancer, and …

Genistein improves bone healing via triggering estrogen receptor alpha-mediated expressions of osteogenesis-associated genes and consequent maturation of …

GJ Wu, JT Chen, YG Cherng, CC Chang… - Journal of Agricultural …, 2020 - ACS Publications
Osteoporosis-associated fractures may cause higher morbidity and mortality. Our previous
study showed the effects of genistein, a phytoestrogen, on the induction of estrogen receptor …

Protective Effect of Genistein on Condylar Cartilage through Downregulating NF‐κB Expression in Experimentally Created Osteoarthritis Rats

J Yuan, W Ding, N Wu, S Jiang… - BioMed research …, 2019 - Wiley Online Library
Temporomandibular joint osteoarthrosis (TMJOA) is characterised by chronic inflammatory
changes, with subsequent gradual loss of joint cartilage. NF‐κB is a crucial transcription …

Valuable food molecules with potential benefits for human health

LC Salanță, A Uifălean, CA Iuga… - The Health Benefits …, 2020 - books.google.com
The rapid development in the food supply chain has led to increased interest for quality in
the food sector. In the last two decades, the human health and food safety have become …

Tectoridin inhibits osteoclastogenesis and bone loss in a murine model of ovariectomy-induced osteoporosis

J Wang, Y Tang, X Lv, J Zhang, B Ma, X Wen… - Experimental …, 2020 - Elsevier
Osteoporosis is a systemic disease that typically affects older adults and that remains a
major threat to global public health owing to its high morbidity and mortality rates. In those …

Benincasa hispida Extract Promotes Proliferation, Differentiation, and Mineralization of MC3T3-E1 Preosteoblasts and Inhibits the Differentiation of RAW 246.7 …

YE Choi, JM Yang, JH Cho - Applied Sciences, 2022 - mdpi.com
Owing to global population aging, instances of bone metabolic diseases have increased.
Consequently, interest in natural and functional plant food products for the prevention and …

Genistein Supplementation and Bone Health in Breast Cancer in Rats

D Skrajnowska, W Bielecki, A Szterk, K Ofiara… - Nutrients, 2024 - mdpi.com
The aim of our study was to analyse the effect of supplementation with various forms of
genistein (nano-, micro-, and macro-) on the mineral status of rat femurs in conditions of …