Indiscriminate antimicrobial use has plagued medicine since antibiotics were first introduced
into clinical practice> 70 years ago. Infectious diseases physicians and public health officials …

Background Improving the quality of hospital antibiotic use is a major goal of WHO's global
action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access …

Neonates are highly susceptible to infections owing to their immature cellular and humoral
immune functions, as well the need for invasive devices. There is a wide practice variation in …

Background Global assessment of antimicrobial agents prescribed to infants in the neonatal
intensive care unit (NICU) may inform antimicrobial stewardship efforts. Methods We …

Background Excessive and inappropriate use of antibiotics in hospitalised patients
contributes to the development and spread of antibiotic resistance. Implementing a …

Objectives In the absence of consensus, the present meta-analysis was performed to
determine an optimal dosing regimen of vancomycin for neonates. Methods A 'meta …

Neonates represent a vulnerable population for infections and neonatal sepsis is a major
cause of mortality and morbidity worldwide. Therefore, antimicrobials are the most …

Background Gastro-oesophageal reflux (GOR) is common in infants. When the condition
causes pathological symptoms and/or complications it is considered gastro-oesophageal …

Background Antimicrobial resistance is increasingly prevalent worldwide. The inappropriate
use of antimicrobials, including in the hospital setting, is considered a major driver of …

Objective The objective is to evaluate the association between antibiotic utilization and
neurodevelopmental outcomes at 18 to 21 months' corrected age among extremely low …