Cardiovascular disease is the leading cause of death in patients with chronic kidney disease
(CKD). As CKD progresses, CKD-specific risk factors, such as disordered mineral …

Klotho is an identified longevity gene with beneficial pleiotropic effects on the kidney.
Evidence shows that a decline in serum Klotho level occurs in early chronic kidney disease …

Background Klotho deficiency is a significant predictor of cardiovascular disease (CVD)-
related mortality and morbidity. However, research assessing the association between …

A series of problems including osteopathy, abnormal serum data, and vascular calcification
associated with chronic kidney disease (CKD) are now collectively called CKD-mineral bone …

This meta-analysis was conducted to clarify the role of klotho and fibroblast growth factor 23
(FGF-23) in human arterial remodeling across recent studies, in terms of arterial calcification …

The role of fibroblast growth factor 23 and Klotho in uremic... : Current Opinion in Nephrology
and Hypertension The role of fibroblast growth factor 23 and Klotho in uremic cardiomyopathy …

Background Klotho, a protein linked to aging, has emerged as a pivotal player in mineral
bone metabolism and might explain the relationship between chronic kidney disease (CKD) …

Background Several experimental studies have demonstrated that fibroblast growth factor
23 (FGF23) may induce myocardial hypertrophy via pathways independent of α-Klotho, its …

Background and aims Abdominal aortic calcification (AAC) has been recognized as an
independent predictor of cardiovascular disease (CVD) incidence and mortality. The aim of …

Results Of 96 screened patients, 78 (mean±SD age: 63±13 years old; 70% men; mean
eGFR: 27±9 ml/min per 1.73 m 2) met the inclusion criteria. At baseline, mean eGFR was …