Entry inhibitors: efficient means to block viral infection

GP Pattnaik, H Chakraborty - The Journal of Membrane Biology, 2020 - Springer
The emerging and re-emerging viral infections are constant threats to human health and
wellbeing. Several strategies have been explored to develop vaccines against these viral …

Measles encephalitis: towards new therapeutics

M Ferren, B Horvat, C Mathieu - Viruses, 2019 - mdpi.com
Measles remains a major cause of morbidity and mortality worldwide among vaccine
preventable diseases. Recent decline in vaccination coverage resulted in re-emergence of …

Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells

L Yi, Z Li, K Yuan, X Qu, J Chen, G Wang… - Journal of …, 2004 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus (SARS-CoV) is the pathogen of SARS,
which caused a global panic in 2003. We describe here the screening of Chinese herbal …

Measles virus fusion protein: structure, function and inhibition

P Plattet, L Alves, M Herren, HC Aguilar - Viruses, 2016 - mdpi.com
Measles virus (MeV), a highly contagious member of the Paramyxoviridae family, causes
measles in humans. The Paramyxoviridae family of negative single-stranded enveloped …

New insights into measles virus brain infections

S Watanabe, Y Shirogane, Y Sato, T Hashiguchi… - Trends in …, 2019 - cell.com
Measles virus (MeV) may persist in the brain, causing fatal neurodegenerative diseases,
subacute sclerosing panencephalitis, and measles inclusion-body encephalitis. However …

Identification of a small-molecule entry inhibitor for filoviruses

A Basu, B Li, DM Mills, RG Panchal… - Journal of …, 2011 - Am Soc Microbiol
Ebola virus (EBOV) causes severe hemorrhagic fever, for which therapeutic options are not
available. Preventing the entry of EBOV into host cells is an attractive antiviral strategy …

Rh (I)–bisphosphine-catalyzed asymmetric, intermolecular hydroheteroarylation of α-substituted acrylate derivatives

CM Filloux, T Rovis - Journal of the American Chemical Society, 2015 - ACS Publications
Asymmetric hydroheteroarylation of alkenes represents a convenient entry to elaborated
heterocyclic motifs. While chiral acids are known to mediate asymmetric addition of electron …

Structures of the prefusion form of measles virus fusion protein in complex with inhibitors

T Hashiguchi, Y Fukuda, R Matsuoka… - Proceedings of the …, 2018 - National Acad Sciences
Measles virus (MeV), a major cause of childhood morbidity and mortality, is highly
immunotropic and one of the most contagious pathogens. MeV may establish, albeit rarely …

Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents

T Ertan, I Yildiz, B Tekiner-Gulbas, K Bolelli… - European journal of …, 2009 - Elsevier
A new series of 5 (or 6)-nitro/amino-2-(substituted phenyl/benzyl) benzoxazole derivatives
(1a–1m, 2a–2l) were synthesized and evaluated for antibacterial and antifungal activities …

Vibrational spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations and computational study of 5-nitro-2-(4-nitrobenzyl) benzoxazole

JB Bhagyasree, HT Varghese, CY Panicker… - … Acta Part A: Molecular …, 2013 - Elsevier
The optimized molecular structure, vibrational frequencies, corresponding vibrational
assignments of 5-nitro-2-(4-nitrobenzyl) benzoxazole have been investigated experimentally …