Atherosclerosis is classed as a disease of aging, such that increasing age is an independent
risk factor for the development of atherosclerosis. Atherosclerosis is also associated with …

Background and aims The aim of this study was to perform a systematic review of the
association between DNA methylation and coronary heart disease (CHD) or related …

Aims We conducted a genome-wide analysis to identify differentially methylated genes in
atherosclerotic lesions. Methods DNA methylation at promoters, exons and introns was …

Life stress has been associated with accelerated cellular aging and increased risk for
developing aging-related diseases; however, the underlying molecular mechanisms remain …

Background Endothelial cell (EC) dysfunctions, including turnover enrichment, gap junction
disruption, inflammation, and oxidation, play vital roles in the initiation of vascular disorders …

Mercury and arsenic are known developmental toxicants. Prenatal exposures are
associated with adverse childhood health outcomes that could be in part mediated by …

Underlying mechanisms of cardiovascular diseases (CVD) have been investigated for over
100 years and novel molecular level mechanisms in the pathophysiology are still …

Vascular aging is a pivotal risk factor promoting vascular dysfunction, the development and
progression of vascular aging-related diseases. The structure and function of endothelial …

Background: Inorganic arsenic (As) may increase the risk of cardiovascular disease (CVD)
and all-cause mortality through accelerated aging, which can be estimated using epigenetic …

Little is known about epigenetics and its possible role in atherosclerosis. We here analysed
histone and DNA methylation and the expression of corresponding methyltransferases in …