Oxytocin, neural plasticity, and social behavior

RC Froemke, LJ Young - Annual Review of Neuroscience, 2021 - annualreviews.org
Oxytocin regulates parturition, lactation, parental nurturing, and many other social behaviors
in both sexes. The circuit mechanisms by which oxytocin modulates social behavior are …

Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

[HTML][HTML] Sex diversity in the 21st century: Concepts, frameworks, and approaches for the future of neuroendocrinology

KO Smiley, KM Munley, K Aghi, SE Lipshutz… - Hormones and …, 2024 - Elsevier
Sex is ubiquitous and variable throughout the animal kingdom. Historically, scientists have
used reductionist methodologies that rely on a priori sex categorizations, in which two …

Breaking through the bottleneck: Krogh's principle in behavioral neuroendocrinology and the potential of gene editing

LR Jackson, MS Lopez, B Alward - Integrative and Comparative …, 2023 - academic.oup.com
Synopsis In 1929, August Krogh wrote that for every question in biology, there is a species
or collection of species in which pursuing such questions is the most appropriate for …

An AAV-CRISPR/Cas9 strategy for gene editing across divergent rodent species: Targeting neural oxytocin receptors as a proof of concept

AJ Boender, M Boon, HE Albers, SR Eck, BA Fricker… - Science …, 2023 - science.org
A major issue in neuroscience is the poor translatability of research results from preclinical
studies in animals to clinical outcomes. Comparative neuroscience can overcome this …

Face individual identity recognition: a potential endophenotype in autism

I Minio-Paluello, G Porciello, A Pascual-Leone… - Molecular Autism, 2020 - Springer
Background Face individual identity recognition skill is heritable and independent of
intellectual ability. Difficulties in face individual identity recognition are present in autistic …

Genetic dissection of steroid-hormone modulated social behavior: Novel paralogous genes are a boon for discovery

BA Alward, AP Hoadley, LR Jackson, MS Lopez - Hormones and behavior, 2023 - Elsevier
Research across species has led to important discoveries on the functions of steroid
hormones in the regulation of behavior. However, like in many fields, advancements in …

Targeted mutation of secretogranin-2 disrupts sexual behavior and reproduction in zebrafish

K Mitchell, WS Zhang, C Lu, B Tao… - Proceedings of the …, 2020 - National Acad Sciences
The luteinizing hormone surge is essential for fertility as it triggers ovulation in females and
sperm release in males. We previously reported that secretoneurin-a, a neuropeptide …

Arginine vasopressin injection rescues delayed oviposition in cyp19a1b -/- mutant female zebrafish

K Shaw, C Lu, X Liu, VL Trudeau - Frontiers in Endocrinology, 2023 - frontiersin.org
In zebrafish, estrogens produced in the ovaries via Cyp19a1a activity are required for both
sexual differentiation of the ovary during early development as well as maintenance of the …

Sex-specific and social experience-dependent oxytocin–endocannabinoid interactions in the nucleus accumbens: implications for social behaviour

AM Borie, LJ Young, RC Liu - … Transactions of the …, 2022 - royalsocietypublishing.org
Oxytocin modulates social behaviour across diverse vertebrate taxa, but the precise nature
of its effects varies across species, individuals and lifetimes. Contributing to this variation is …