It has been more than three decades since the first monoclonal antibody was approved by
the United States Food and Drug Administration (US FDA) in 1986, and during this time …

Laser-assisted microdissection (LAM) is a powerful tool for isolating specific tissues, cell
types and even organelles from sectioned biological specimen in a manner conducive to the …

Deciphering the cellular and molecular interactions that drive disease within the tissue
microenvironment holds promise for discovering drug targets of the future. In order to …

Monoclonal antibodies (mAbs) are arguably the most significant class of biologics for use as
pharmaceuticals and diagnostics. Many technological concepts exist for the generation and …

A technique used to amplify the number of copies of a specific region of DNA, the
polymerase chain reaction (PCR) is at the forefront of the dramatic development of …

The aim of this study was to develop a highly specific and sensitive (RT-) PCR capable of
potentially amplifying the rearranged/expressed VH and VL gene belonging to any mouse …

Monoclonal antibodies (mAbs) are used to prevent, detect, and treat a broad spectrum of
non-communicable and communicable diseases. Over the past few years, the market for …

Chronic infectious diseases of the central nervous system (CNS) are characterized by
intrathecal synthesis of increased amounts of immunoglobulin G (IgG) directed against the …

Recent evidence has shown that the androgen receptor (AR) plays a major role in all
prostate cancer stages, including both androgen-dependent and-independent tumors. A …

The dawn of the 20th century saw the formative years of developments in immunology. In
particular, immunochemistry, specifically pertaining to antibodies, was extensively studied …