Senescent T cells are proliferative disabled lymphocytes that lack antigen-specific
responses. The development of T-cell senescence in autoimmune diseases contributes to …

CD8+ T cells are cytotoxic lymphocytes that destroy pathogen infected and malignant cells
through release of cytolytic molecules and proinflammatory cytokines. Although the role of …

Elderly-onset rheumatoid arthritis (EORA) is associated with higher disease activity and
accelerated joint destruction compared with young-onset RA (YORA). However, the …

With advances in tissue typing, organ preservation techniques, and clinical surgery, organ
transplantation has gained popularity as a treatment option for various end-stage diseases …

Introduction The peripheral immune system changes in amyotrophic lateral sclerosis (ALS),
but the causal relationship between the two is still controversial. Methods In this study, we …

Aim: To investigate the relationship between potential abnormal epigenetic modification and
immune cell infiltration in patients with cervical carcinoma. Materials & methods: RNA …

Diagnosis of systemic lupus erythematosus (SLE) in childhood [juvenile-onset (J) SLE],
results in a more severe disease phenotype including major organ involvement, increased …

Multiple sclerosis (MS) is the main reason for disability caused by autoimmunity. However,
effective biomarkers for MS have not been identified. This study explored the molecular …

Sepsis is the leading systemic inflammatory response syndrome in worldwide, yet relatively
little is known about the genes and signaling pathways involved in sepsis progression. The …

The aim of our study was to investigate the main characteristics of peripheral blood NKT cell
phenotype in patients with disseminated purulent peritonitis (DPP) in dynamics of …