Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases
CG Gottschalk, D Peterson, J Armstrong, K Knox… - Infectious agents and …, 2023 - Springer
Historically, COVID-19 emerges as one of the most devastating diseases of humankind,
which creates an unmanageable health crisis worldwide. Until now, this disease costs …
which creates an unmanageable health crisis worldwide. Until now, this disease costs …
Roseolovirus molecular biology: recent advances
LT Krug, PE Pellett - Current opinion in virology, 2014 - Elsevier
Highlights•HHV-6A, HHV-6B, and HHV-7 are distinct members of the roseolovirus
genus.•HHV-6A and HHV-6B can integrate into the telomeres of the host chromosome.•Lytic …
genus.•HHV-6A and HHV-6B can integrate into the telomeres of the host chromosome.•Lytic …
Complete genome sequence of germline chromosomally integrated human herpesvirus 6A and analyses integration sites define a new human endogenous virus with …
Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous
genomes, resulting from integration into the germline: chromosomally-integrated “CiHHV …
genomes, resulting from integration into the germline: chromosomally-integrated “CiHHV …
Analysis of herpesvirus infection and genome single nucleotide polymorphism risk factors in multiple sclerosis, Volga federal district, Russia
V Lezhnyova, Y Davidyuk, A Mullakhmetova… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a heterogeneous disease where herpesvirus infection and genetic
predisposition are identified as the most consistent risk factors. Serum and blood samples …
predisposition are identified as the most consistent risk factors. Serum and blood samples …
Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling
Z Wu, J Jia, X Xu, M Xu, G Peng, J Ma, X Jiang… - PLoS …, 2020 - journals.plos.org
Human herpesvirus 6 (HHV-6) is an important immunosuppressive and immunomodulatory
virus worldwide. However, whether and how HHV-6 infection influences the metabolic …
virus worldwide. However, whether and how HHV-6 infection influences the metabolic …
A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion
SJ Patel, G Zhao, VR Penna, E Park, EJ Lauron… - Journal of …, 2017 - Am Soc Microbiol
The human roseoloviruses human herpesvirus 6A (HHV-6A), HHV-6B, and HHV-7 comprise
the Roseolovirus genus of the human Betaherpesvirinae subfamily. Infections with these …
the Roseolovirus genus of the human Betaherpesvirinae subfamily. Infections with these …
Immune response to HHV-6 and implications for immunotherapy
A Becerra, L Gibson, LJ Stern, JM Calvo-Calle - Current opinion in virology, 2014 - Elsevier
Highlights•Chronic HHV-6 infection is controlled by antibody and T cell immune
responses.•Post-transplantation immunosuppression allows HHV-6 reactivation and …
responses.•Post-transplantation immunosuppression allows HHV-6 reactivation and …
HHV-6B infection, T-cell reconstitution, and graft-vs-host disease after hematopoietic stem cell transplantation
Successful and sustained CD4+ T-cell reconstitution is associated with increased survival
after hematopoietic cell transplantation (HCT), but opportunistic infections may adversely …
after hematopoietic cell transplantation (HCT), but opportunistic infections may adversely …
Advances in the characterization of the T-cell response to human herpesvirus-6
Human herpesvirus (HHV) 6 is thought to remain clinically latent in most individuals after
primary infection and to reactivate to cause disease in persons with severe …
primary infection and to reactivate to cause disease in persons with severe …
Roseoloviruses and their modulation of host defenses
AW Hudson - Current opinion in virology, 2014 - Elsevier
Highlights•The host antiviral response is sophisticated and the host is well-equipped to
eradicate viruses.•The β-herpesviruses have evolved mechanisms to undermine host …
eradicate viruses.•The β-herpesviruses have evolved mechanisms to undermine host …