Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Diffusion tensor imaging (DTI) allows measuring fractional anisotropy and similar
microstructural indices of the brain white matter. Lower than normal fractional anisotropy as …

Parkinson's disease involves multiple neurotransmitter systems beyond the classical
dopaminergic circuit, but their influence on structural and functional alterations is not well …

Fine particulate air pollution (PM 2.5) exposures are linked with Alzheimer's and Parkinson's
diseases (AD, PD). AD and PD neuropathological hallmarks are documented in children …

Background The subthalamic nucleus (STN) is considered a key structure in motor,
behavioral, and emotional control. Although identification of the functional topography of the …

The global fractional anisotropy (gFA) is a structural marker of white matter myelination and
integrity. Previous studies already evidenced that aging-related reduced integrity of specific …

The progression of Parkinson's disease (PD) is associated with microstructural alterations in
neural pathways, contributing to both motor and cognitive decline. However, conflicting …

Assessing the consistency of quantitative MRI measurements is critical for inclusion in
longitudinal studies and clinical trials. Intraclass coefficient correlation and coefficient of …

Background Parkinson's disease (PD) is the second most common neurodegenerative
disorder. Early detection is crucial for treatment and slowing disease progression …

Simple Summary This article reviews the use of diffusion tensor imaging (DTI) to evaluate
changes in white matter microstructure within two specific fiber tracts in Parkinson's disease …