Antibacterial activities with the structure-activity relationship of coumarin derivatives

HL Qin, ZW Zhang, L Ravindar, KP Rakesh - European journal of medicinal …, 2020 - Elsevier
The development of drug-resistant bacteria, as well as multidrug-resistant pathogens related
to substantial mortality, is an important global health threat. The wide range of biological …

New progress in azole compounds as antimicrobial agents

HZ Zhang, LL Gan, H Wang… - Mini reviews in medicinal …, 2017 - ingentaconnect.com
The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity

DS Reddy, M Kongot, A Kumar - Tuberculosis, 2021 - Elsevier
Tuberculosis (TB) is a highly contagious airborne disease with nearly 25% of the world's
population infected with it. Challenges such as multi drug resistant TB (MDR-TB), extensive …

Antibacterial pyrazoles: Tackling resistant bacteria

MA Alam - Future Medicinal Chemistry, 2022 - Taylor & Francis
Bacterial resistance to antibiotics threatens our progress in healthcare, modern medicine,
food production and ultimately life expectancy. Antibiotic resistance is a global concern …

3-(Bromoacetyl) coumarins: unraveling their synthesis, chemistry, and applications

MM Abdou, A Abu-Rayyan, AG Bedir, S Abdel-Fattah… - RSC …, 2021 - pubs.rsc.org
This review emphasizes recent developments in synthetic routes of 3-(bromoacetyl)
coumarin derivatives. Also, chemical reactions of 3-(bromoacetyl) coumarins as versatile …

Synthesis of (Z)-1-(1, 3-diphenyl-1H-pyrazol-4-yl)-3-(phenylamino) prop-2-en-1-one derivatives as potential anticancer and apoptosis inducing agents

TS Reddy, VG Reddy, H Kulhari, R Shukla… - European Journal of …, 2016 - Elsevier
Abstract A series of (Z)-1-(1, 3-diphenyl-1H-pyrazol-4-yl)-3-(phenylamino) prop-2-en-1-one
derivatives were synthesized and characterized by 1 H and 13 C NMR, ESI-MS and HRMS …

A facile synthesis and evaluation of new biomolecule-based coumarin–thiazoline hybrids as potent anti-tubercular agents with cytotoxicity, DNA cleavage and X-ray …

DS Reddy, KM Hosamani, HC Devarajegowda… - RSC Advances, 2015 - pubs.rsc.org
An efficient and rapid synthesis of coumarin–thiazoline hybrids (1a–1j) under microwave
irradiation is described with high yields. The synthesized compounds were characterized …

Design, Synthesis, Cytotoxicity Profiling, Molecular Docking and ADMET Studies of Novel Functionalized Coumarin-pyrazole-thiazole Hybrids: Cyclization of …

TE Ali, AK Alsolimani, MA Assiri, AA Shati… - Current Organic …, 2025 - benthamdirect.com
A simple synthetic method was performed to design a novel series of polycyclic systems
consisting of a coumarin-pyrazole-thiazole skeleton linked with a completed thiazole ring via …

Novel Coumarin‐Pyrazole‐Thiazoles Hybrids: Synthesis, Anticancer Activity, Molecular Docking and In Silico ADMET prediction Studies

AK Alsolimani, TE Ali, MA Assiri, AA Shati… - …, 2024 - Wiley Online Library
A novel series of coumarin‐pyrazole‐thiazoles hybrids was designed. The methodology
depended on a simple condensation reaction of 3‐(2‐oxo‐2H‐chromen‐3‐yl)‐1‐phenyl‐1H …

Efficient syntheses and antimicrobial activities of new thiophene containing pyranone and quinolinone derivatives using manganese (III) acetate: the effect of …

M Özgür, M Yılmaz, H Nishino, EÇ Avar, H Dal… - New Journal of …, 2019 - pubs.rsc.org
The syntheses of a new series of pyranones, namely, fused pyranones and quinoline-based
dihydrofurans, accompanied by 3-alkenyl-substituted structures were investigated. The …