Relevant reviews highlight the association between dysfunctional mitochondria and
inflammation, but few studies address the contribution of mitochondria and mitochondria …

Neurodegenerative diseases comprise a wide spectrum of pathologies characterized by
progressive loss of neuronal functions and structures. Despite having different genetic …

Loss of function in mitochondria, the key organelle responsible for cellular energy
production, can result in the excess fatigue and other symptoms that are common complaints …

Multiple sclerosis (MS) is a relatively common and etiologically unknown disease with no
cure treatment. It is the leading cause of neurological disability in young adults, affecting …

Abstract Dynamin-related protein (Drp) 1 is a key regulator of mitochondrial fission and is
composed of GTP-binding, Middle, insert B, and C-terminal GTPase effector (GED) domains …

Reactive oxygen species (ROS) act physiologically as signaling molecules. In pathological
conditions, such as ischemic stroke, ROS are released in excessive amounts and upon …

Mitochondrial defects, affecting parameters such as mitochondrial number and shape, levels
of respiratory chain complex components and markers of oxidative stress, have been …

Psychiatrists empirically recognize that excessive or chronic psychological stress can result
in long‐lasting impairments of brain functions that partly involve neuronal cell damage …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS). There is increasing evidence that MS is not only characterized by immune mediated …

Auto-inflammatory and autoimmune diseases of the musculoskeletal system can be
perceived as a spectrum of rheumatic diseases, with the joints and connective tissues are …