Advances in developing ACE2 derivatives against SARS-CoV-2

H Zhang, P Lv, J Jiang, Y Liu, R Yan, S Shu… - The Lancet …, 2023 - thelancet.com
Extensive immune evasion of SARS-CoV-2 rendered therapeutic antibodies ineffective in
the COVID-19 pandemic. Propagating SARS-CoV-2 variants are characterised by immune …

Lipid nanoparticles as promising carriers for mRNA vaccines for viral lung infections

M Hajiaghapour Asr, F Dayani, F Saedi Segherloo… - Pharmaceutics, 2023 - mdpi.com
In recent years, there has been an increase in deaths due to infectious diseases, most
notably in the context of viral respiratory pathogens. Consequently, the focus has shifted in …

Nanomedicine in lung cancer immunotherapy

M Doroudian, S Zanganeh… - … in bioengineering and …, 2023 - frontiersin.org
Lung cancer is the major cause of cancer death worldwide. Cancer immunotherapy has
been introduced as a promising and effective treatment that can improve the immune …

Molecular insight into the therapeutic effects of stem cell-derived exosomes in respiratory diseases and the potential for pulmonary delivery

MH Azhdari, N Goodarzi, M Doroudian… - International Journal of …, 2022 - mdpi.com
Respiratory diseases are the cause of millions of deaths annually around the world. Despite
the recent growth of our understanding of underlying mechanisms contributing to the …

Drug repositioning in the COVID-19 pandemic: fundamentals, synthetic routes, and overview of clinical studies

ES Vaz, SV Vassiliades, J Giarolla, MC Polli… - European Journal of …, 2023 - Springer
Introduction Drug repositioning is a strategy to identify a new therapeutic indication for
molecules that have been approved for other conditions, aiming to speed up the traditional …

The current landscape of glioblastoma biomarkers in body fluids

S Zanganeh, E Abbasgholinejad, M Doroudian… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma is a highly aggressive brain cancer, and early detection and
accurate diagnosis are crucial for effective treatment. Traditional diagnostic methods have …

Aptamers targeting membrane proteins for sensor and diagnostic applications

N Kara, N Ayoub, H Ilgu, D Fotiadis, M Ilgu - Molecules, 2023 - mdpi.com
Many biological processes (physiological or pathological) are relevant to membrane
proteins (MPs), which account for almost 30% of the total of human proteins. As such, MPs …

Functional foods: a promising strategy for restoring gut microbiota diversity impacted by SARS-CoV-2 variants

A Banerjee, I Somasundaram, D Das, S Jain Manoj… - Nutrients, 2023 - mdpi.com
Natural herbs and functional foods contain bioactive molecules capable of augmenting the
immune system and mediating anti-viral functions. Functional foods, such as prebiotics …

Neurological complications associated with Covid‐19; molecular mechanisms and therapeutic approaches

M Mahboubi Mehrabani, MS Karvandi… - Reviews in medical …, 2022 - Wiley Online Library
With the progression of investigations on the pathogenesis of severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), neurological complications have emerged as a …

Viral Nanoparticles‐Mediated Delivery of Therapeutic Cargo

S Zanganeh, M Doroudian, ZR Nowzari… - Advanced …, 2023 - Wiley Online Library
The rapid advancement of nanotechnology in recent years has opened new avenues of
investigation for biomedical sciences. Viral nanoparticles (VNPs) are formulated from plant …