Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention

P Karimi, F Islami, S Anandasabapathy… - … , biomarkers & prevention, 2014 - AACR
Less than a century ago, gastric cancer was the most common cancer in the United States
and perhaps throughout the world. Despite its worldwide decline in incidence over the past …

Genetics of gastric cancer

MH McLean, EM El-Omar - Nature reviews Gastroenterology & …, 2014 - nature.com
Gastric cancer remains highly prevalent and accounts for a notable proportion of global
cancer mortality. This cancer is also associated with poor survival rates. Understanding the …

The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk

DD Wang, LH Nguyen, Y Li, Y Yan, W Ma, E Rinott… - Nature medicine, 2021 - nature.com
To address how the microbiome might modify the interaction between diet and
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …

The airway microbiome mediates the interaction between environmental exposure and respiratory health in humans

L Lin, X Yi, H Liu, R Meng, S Li, X Liu, J Yang, Y Xu… - Nature Medicine, 2023 - nature.com
Exposure to environmental pollution influences respiratory health. The role of the airway
microbial ecosystem underlying the interaction of exposure and respiratory health remains …

Gastric cancer—molecular and clinical dimensions

R Wadhwa, S Song, JS Lee, Y Yao, Q Wei… - Nature reviews Clinical …, 2013 - nature.com
Gastric cancer imposes a considerable health burden around the globe despite its declining
incidence. The disease is often diagnosed in advanced stages and is associated with a poor …

Gastric cancer: epidemiology, biology, and prevention: a mini review

K Lyons, LC Le, YTH Pham, C Borron… - European Journal of …, 2019 - journals.lww.com
Gastric cancer is one of the most common causes of cancer-related mortality worldwide. The
objective of this article is to review the epidemiology and biology of gastric cancer risk. This …

Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori …

K Lertpiriyapong, MT Whary, S Muthupalani, JL Lofgren… - Gut, 2014 - gut.bmj.com
Objectives Gastric colonisation with intestinal flora (IF) has been shown to promote
Helicobacter pylori (Hp)-associated gastric cancer. However, it is unknown if the mechanism …

GRASP: analysis of genotype–phenotype results from 1390 genome-wide association studies and corresponding open access database

R Leslie, CJ O'Donnell, AD Johnson - Bioinformatics, 2014 - academic.oup.com
We created a deeply extracted and annotated database of genome-wide association studies
(GWAS) results. GRASP v1. 0 contains> 6.2 million SNP-phenotype association from among …

Helicobacter pylori infection causes both protective and deleterious effects in human health and disease

AK Miller, SM Williams - Genes & Immunity, 2021 - nature.com
Infection with Helicobacter pylori (H. pylori) is necessary but not sufficient for the
development of gastric cancer, the third leading cause of cancer death globally. H. pylori …

A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11. 23

Y Li, K Zhang, H Chen, F Sun, J Xu, Z Wu, P Li… - Nature …, 2013 - nature.com
Primary Sjögren's syndrome is one of the most common autoimmune diseases. So far,
genetic studies of Sjögren's syndrome have relied mostly on candidate gene approaches …