Comparative efficacy and acceptability of pharmacological, psychological, and neurostimulatory interventions for ADHD in adults: a systematic review and component …

EG Ostinelli, M Schulze, C Zangani, LC Farhat… - The Lancet …, 2025 - thelancet.com
Background The comparative benefits and harms of available interventions for ADHD in
adults remain unclear. We aimed to address these important knowledge gaps. Methods In …

[HTML][HTML] Enhancing Acute Migraine Treatment: Exploring Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for the Nose-to-Brain Route

J Torres, R Silva, G Farias, JM Sousa Lobo… - Pharmaceutics, 2024 - mdpi.com
Migraine has a high prevalence worldwide and is one of the main disabling neurological
diseases in individuals under the age of 50. In general, treatment includes the use of oral …

Regional distribution of unbound eletriptan and sumatriptan in the CNS and PNS in rats: implications for a potential central action

N Svane, F Bällgren, A Ginosyan, M Kristensen… - The Journal of …, 2024 - Springer
Background Triptans are potent 5-HT1B/1D/1F receptor agonists used in migraine therapy,
thought to act through peripheral mechanisms. It remains unclear whether triptans cross the …

Real-world study of adverse events associated with triptan use in migraine treatment based on the US Food and Drug Administration (FDA) adverse event reporting …

WH Liu, HM Hu, C Li, Q Shi, CH Liu, AX Liu… - The Journal of …, 2024 - Springer
Abstract Background Triptans selectively agoniste 5-Hydroxytryptamine (5-HT) receptors
and are widely used in the treatment of migraine. Nevertheless, there is a dearth of …

Understanding the efficacy and tolerability of migraine treatment: a deep dive into CGRP antagonists

M Waliszewska-Prosół, B Raffaelli… - Expert Review of …, 2024 - Taylor & Francis
Introduction The discovery of the role of the calcitonin gene-related peptide (CGPR) in
migraine pathogenesis ushered in a new era in headache medicine. This evidence led to …

Any NHS reform has to avoid a repeat of 2012

T Moberly - 2024 - bmj.com
After 44 days of strike action over the past two years, resident doctors (as junior doctors will
now be known) have voted to accept the government's latest pay offer, with two thirds of …

Neues zur medikamentösen Therapie akuter Migräneattacken: Triptane, Gepante und Ditane

HC Diener, U Reuter - DGNeurologie, 2024 - Springer
Viele Patienten können erfolgreich ihre leichten oder mittelschweren Migräneattacken mit
Analgetika oder nichtsteroidalen Antirheumatika behandeln. Die meisten dieser …

[PDF][PDF] I triptani sono più efficaci rispetto ai trattamenti convenzionali ea quelli innovativi nella gestione degli episodi di emicrania acuta

PK Kurotschka, D Slawson… - Recenti Progressi in …, 2025 - researchgate.net
I triptani sono più efficaci rispetto ai trattamenti convenzionali ea quelli innovativi nella
gestione degli episodi di emic Page 1 POEMs Recenti Prog Med 2025; 116: 53-54 53 …

[PDF][PDF] Ruolo chiave del CGRP nella fisiopatologia e profilassi dell'emicrania-EPTINEZUMAB: primo mAb a somministrazione endovenosa rimborsabile in Italia.

EF GASPARONE - 2023 - unitesi.uniupo.it
1. Peptide correlato al gene della calcitonina (CGRP) pag. 65 1.1. Struttura molecolare del
peptide ³-CGRP e meccanismo d9azione pag. 67 1.2. Recettore del CGRP e legame CGRP …

[HTML][HTML] Headache & Migraine

J Smith - community.the-hospitalist.org
A rare coin-shaped headache long viewed as a primary headache disorder frequently has
underlying causes, according to new research, and clinicians should refer people who …