Transforming growth factor β (TGF-β) is a secreted cytokine that regulates cell proliferation,
migration, and the differentiation of a plethora of different cell types. Consistent with these …

Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …

Recent studies suggest that the majority of the human genome is transcribed, but only about
2% accounts for protein-coding exons. Long noncoding RNAs (lncRNAs) constitute a …

Metastasis is the primary cause of cancer-related death all over the world. Metastasis is a
process by which cancer spreads from the place at which it first arose to distant locations in …

Background Tumors contain a functional subpopulation of cells that exhibit stem cell
properties. These cells, named cancer stem cells (CSCs), play significant roles in the …

Epithelial–mesenchymal transition (EMT) is a multistep process that allows epithelial cells to
acquire mesenchymal properties. Fundamental in the early stages of embryonic …

Anastomotic leak (AL) constitutes a significant issue in colorectal surgery, and its incidence
has remained stable over the last years. The use of intra-abdominal drain or the use of …

Gastric cancer (GC) was the fourth deadliest cancer in the world in 2020, and about 770,000
people died from GC that year. The death of patients with GC is mainly caused by the …

Noncoding RNAs (ncRNAs) have been demonstrated to closely associate with gene
regulation and encompass the well-known microRNAs (miRNAs), as well as the most …

Long non-coding RNAs (lncRNAs) are members of the non-protein coding RNA family
longer than 200 nucleotides. They participate in the regulation of gene and protein …