Sensors are devices that respond to physical or chemical stimuli and produce detectable
signals. 1r4 They are a critical extension of human perception of the world in many aspects …

SELEX stands for systematic evolution of ligands by exponential enrichment. This method,
described primarily in 1990 [Ellington, AD, Szostak, JW, 1990. In vitro selection of RNA …

Nucleic acid aptamers are single stranded DNA or RNA sequences that specifically bind a
cognate ligand. In addition to their widespread use as stand-alone affinity binding reagents …

Aptamers are single stranded oligonucleotides that bind a wide range of biological targets.
Although aptamers can be isolated from pools of random sequence oligonucleotides using …

DNA is one of the most promising materials for nanobiotechnology, and the present review
article aims to describe recent advances in the self-assembly of functional DNA …

Infectious diseases are a serious global problem, which not only take an enormous human
toll but also incur tremendous economic losses. In combating infectious diseases, rapid and …

Aptamers have been widely used as recognition elements for biosensor construction,
especially in the detection of proteins or small molecule targets, and regarded as promising …

Conspectus The biosensor community has long focused on achieving the lowest possible
detection limits, with specificity (the ability to differentiate between closely similar target …

Aptamers are useful for allosteric regulation because they are nucleic acid–based structures
in which ligand binding induces conformational changes that may alter the function of a …

An approach is developed to detect the organophosphorus pesticides via competitive
binding to a recombinant broad-specificity DNA aptamer with a molecular beacon (MB), the …