A review of ligand-based virtual screening web tools and screening algorithms in large molecular databases in the age of big data

AJ Banegas-Luna, JP Cerón-Carrasco… - Future medicinal …, 2018 - Taylor & Francis
Virtual screening has become a widely used technique for helping in drug discovery
processes. The key to this success is its ability to aid in the identification of novel bioactive …

Role of Natural Compounds and Target Enzymes in the Treatment of Alzheimer's Disease

S Wang, X Kong, Z Chen, G Wang, J Zhang, J Wang - Molecules, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurological condition. The rising prevalence of
AD necessitates the rapid development of efficient therapy options. Despite substantial …

Vincamine, a safe natural alkaloid, represents a novel anticancer agent

S Al-Rashed, A Baker, SS Ahmad, A Syed… - Bioorganic …, 2021 - Elsevier
Vincamine, a well-known plant alkaloid, has been used as a dietary supplement and as a
peripheral vasodilator to combat aging in humans. In this study, for the very first time, we …

Interaction study of dietary fibers (pectin and cellulose) with meat proteins using bioinformatics analysis: An In-Silico study

SS Ahmad, M Khalid, K Younis - LWT, 2020 - Elsevier
As meat is deficient in dietary fiber, it is combined with different dietary fibers from cereals,
fruits, and vegetables. Interactions of pectin and cellulose with actin, myosin, and collagen …

Study of Caspase 8 inhibition for the management of Alzheimer's disease: a molecular docking and dynamics simulation

SS Ahmad, M Sinha, K Ahmad, M Khalid, I Choi - Molecules, 2020 - mdpi.com
Alzheimer's disease (AD) is the most common type of dementia and usually manifests as
diminished episodic memory and cognitive functions. Caspases are crucial mediators of …

What is blockchain technology and its significance in the current healthcare system? A brief insight

SS Ahmad, S Khan, MA Kamal - Current pharmaceutical design, 2019 - ingentaconnect.com
Background: The promising eventual fate of blockchain in healthcare has a lot more
extensive prospect. Blockchain is a novel structure that gives another design to storage and …

Mitochondrial dynamics and proteins related to neurodegenerative diseases

A Alexiou, B Nizami, FI Khan, G Soursou… - Current Protein and …, 2018 - ingentaconnect.com
Disruptions in the regulation of mitochondrial dynamics and the occurrence of proteins
misfolding lead to neuronal death, resulting in Age-related Dementia and …

Potentially bioactive fungus mediated silver nanoparticles

A Baker, S Iram, A Syed, AM Elgorban, AM Al-Falih… - Nanomaterials, 2021 - mdpi.com
Fungal metabolites, proteins, and enzymes have been rich sources of therapeutics so far.
Therefore, in this study, the hypha extract of a newly identified noble fungus (Alternaria sp …

Study of nutraceuticals and phytochemicals for the management of Alzheimer's disease: A review

SS Ahmad, M Khalid, MA Kamal… - Current …, 2021 - benthamdirect.com
Background: Alzheimer's disease (AD) affects several people worldwide and has
devastating impacts on society with a limited number of approaches for its pharmacological …

Computational study of natural compounds for the clearance of amyloid-βeta: A potential therapeutic management strategy for Alzheimer's Disease

SS Ahmad, H Khan, SM Danish Rizvi, SA Ansari… - Molecules, 2019 - mdpi.com
Alzheimer's disease (AD) is a widespread dynamic neurodegenerative malady. Its etiology
is still not clear. One of the foremost pathological features is the extracellular deposits of …