ABSTRACT A vast array of oncogenic variants has been identified for anaplastic lymphoma
kinase (ALK). Therefore, there is a need to better understand the role of ALK in cancer …

The burgeoning field of anaplastic lymphoma kinase (ALK) in cancer encompasses many
cancer types, from very rare cancers to the more prevalent non-small-cell lung cancer …

Lipid nanoparticles (LNPs) are the leading nonviral technologies for the delivery of
exogenous RNA to target cells in vivo. As systemic delivery platforms, these technologies …

RTKs (receptor tyrosine kinases) play important roles in cellular proliferation and
differentiation. In addition, RTKs reveal oncogenic potential when their kinase activities are …

Neural crest cells are highly multipotent stem cells, but it remains unclear how their fate
restriction to specific fates occurs. The direct fate restriction model hypothesises that …

Vertebrate pigment patterns are diverse and fascinating adult traits that allow animals to
recognize conspecifics, attract mates, and avoid predators. Pigment patterns in fish are …

Colour patterns are prominent features of many animals and have important functions in
communication, such as camouflage, kin recognition and mate choice. As targets for natural …

The anaplastic lymphoma kinase (ALK) gene plays an important physiologic role in the
development of the brain and can be oncogenically altered in several malignancies …

Colour patterns of adult fish are produced by several types of pigment cells that distribute in
the dermis during juvenile development. The zebrafish, Danio rerio, displays a striking …

More than half a century ago, Alan Turing postulated that pigment patterns may arise from a
mechanism that could be mathematically modeled based on the diffusion of two substances …