Nasopharyngeal carcinoma (NPC) is a malignant epithelial carcinoma of the head and neck
region which mainly distributes in southern China and Southeast Asia and has a crucial …

Epstein–Barr virus-associated diseases are important global health concerns. As a group I
carcinogen, EBV accounts for 1.5% of human malignances, including both epithelial-and …

Cancer is commonly thought to be the product of irregular cell division. According to the
World Health Organization (WHO), cancer is the major cause of death globally. Nature offers …

Abstract Stephania tetrandra S. Moore (S. tetrandra) is distributed widely in tropical and
subtropical regions of Asia and Africa. The root of this plant is known in Chinese as “Fen …

Autophagy and endoplasmic reticulum (ER) stress are conserved processes that generally
promote survival, but can induce cell death when physiological thresholds are crossed. The …

Objectives To investigate the antitumour property of tetrandrine by inducing autophagy and
apoptosis in human gastric cancer cells, and to explore the potential molecular mechanisms …

Tetrandrine, a lead anti-tumor compound with a bis-benzyltetrahydroisoquinoline skeleton
isolated from medicinal plant Stephania tetrandra. In order to obtain active anti-tumor agents …

Irinotecan (IRI), an anticancer drug to treat colon cancer patients, causes cytotoxic effects on
normal cells. Phenethyl isothiocyanate (PEITC), rich in common cruciferous plants, has …

The aim of this study was to investigate the effects of bufalin on human nasopharyngeal
carcinoma NPC-TW 076 cells in vitro. Bufalin is a cardiotonic steroid and a key active …

Background Endometrial cancer (EC) is one of the most common gynaecological
malignancies, and its incidence has been rising over the past decade. Tetrandrine, a …