The brain is an intricate network with complex organizational principles facilitating a
concerted communication between single-neurons, distinct neuron populations, and remote …

INTRODUCTION Mutations of the X-linked Protocadherin-19 (PCDH19) gene cause
PCDH19 disorder with epilepsy. PCDH19 disorder is often associated with cognitive …

Sensors, biosensors, lateral flow immunoassays, portable thin-layer chromatography and
similar devices for hand-held assay are tools suitable for field or out of laboratories assays of …

Multiple genetic, metabolic, and environmental abnormalities are known to contribute to the
pathogenesis of Alzheimer's dementia (AD). If all of those abnormalities were addressed it …

Resolving fundamental molecular and functional processes underlying human synaptic
development is crucial for understanding normal brain function as well as dysfunction in …

Used as a supplement to psychotherapy, pharmacotherapy that addresses all of the known
metabolic and genetic contributions to the pathogenesis of psychiatric conditions caused by …

In the field of neurodegenerative pathologies, the platforms for disease modelling based on
patient-derived induced pluripotent stem cells (iPSCs) represent a valuable molecular …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
amyloid plaques and cognitive decline, the latter of which is thought to be driven by soluble …

A variety of in vitro assays have been designed based on optical imaging to study essential
processes for nervous system development, such as neurogenesis and synaptogenesis …

Background Pharmacotherapy for most psychiatric conditions was developed from
serendipitous observations of benefit from drugs prescribed for different reasons. An …