Alzheimer's disease (AD) is a complex neurodegenerative disease in the elderly and the
most common cause of human dementia. AD is characterized by accumulation of abnormal …

In multicellular organisms, cell death is a critical and active process that maintains tissue
homeostasis and eliminates potentially harmful cells. There are three major types of …

Thousands of loci in the human and mouse genomes give rise to circular RNA transcripts; at
many of these loci, the predominant RNA isoform is a circle. Using an improved …

Perturbation of endoplasmic reticulum (ER) homeostasis results in a stress condition termed
“ER stress” determining the activation of a finely regulated program defined as unfolded …

Autophagy is a major degradative process activated in a rapid and transient manner to cope
with stress conditions. Whether autophagy is beneficial or detrimental depends upon the …

Arginine, one among the 20 most common natural amino acids, has a pivotal role in cellular
physiology as it is being involved in numerous cellular metabolic and signaling pathways …

Autophagy represents an intracellular degradation process which is involved in both cellular
homeostasis and disease settings. In the last two decades, the molecular machinery …

Sarcopenia is a severe loss of muscle mass and functional decline during aging that can
lead to reduced quality of life, limited patient independence, and increased risk of falls. The …

Hepatitis C virus (HCV) is a major leading cause of hepatocellular carcinoma (HCC). HCV-
induced hepatocarcinogenesis is a multistep process resulting from a combination of …

Mitochondria (MT), the major site of cellular energy production, are under dual genetic
control by 37 mitochondrial DNA (mtDNA) genes and numerous nuclear genes (MT-nDNA) …