The intricate physiology of many Central Nervous System (CNS) disorders points towards
oxidative damages of neurons. Various studies have established that oxidative stress is a …

The incidence of metabolic disorders, as well as of neurodegenerative diseases—mainly the
sporadic forms of Alzheimer's and Parkinson's disease—are increasing worldwide. Notably …

Purpose It has been supposed that cardiac toxicity of doxorubicin is due to its production of
free radicals and inflammatory cytokines. Dapsone, an antibiotic drug which is the principal …

Blood-brain barrier (BBB) function deteriorates during aging, contributing to cognitive
impairment and neurodegeneration. It is unclear what drives BBB leakage in aging and how …

The metabolic syndrome has been associated to chronic peripheral inflammation and
related with neuroinflammation and neurodegeneration, including Parkinson's disease …

Myocardial infarction (MI) is a critical condition that can happen with high doses or rapid
termination of beta blockers therapy. The study aimed to evaluate the potential anti-toxic …

Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) often leads to
aggressive local recurrence and increased metastasis, and vascular integrity and platelets …

Background Osteomyelitis is a severe bone infection and typically leads to progressive bone
resorption, destruction and dysfunction. Pyroptosis is a form of programmed cell death …

Abstract The 4, 4′-diaminodiphenyl sulfone (DDS), also known as dapsone, is traditionally
used as a potent anti-bacterial agent in clinical management of leprosy. For decades …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces immune-mediated
type 1 interferon (IFN-1) production, the pathophysiology of which involves sterile alpha …