Although Rett syndrome (RTT) represents one of the most frequent forms of severe
intellectual disability in females worldwide, we still have an inadequate knowledge of the …

The retinoblastoma tumor suppressor protein (pRB) plays an integral role in G1-S
checkpoint control and consequently is a frequent target for inactivation in cancer. The RB …

Most cancer-related deaths come from metastasis. It was recently discovered that
nanoparticles could inhibit cancer cell migration. Whereas most researchers focus on single …

Meat tenderness prediction is a challenging task, especially in Maremmana, an Italian
autochtonous and highly appreciated beef breed. In the present study we reported an …

How repetitive elements, epigenetic modifications, and architectural proteins interact
ensuring proper genome expression remains poorly understood. Here, we report regulatory …

G protein‐coupled estrogen receptor‐1 (GPER), a member of the G protein‐coupled
receptor (GPCR) superfamily, mediates estrogen‐induced proliferation of normal and …

A synergy between β-amyloid (Aβ) and tau appears to occur in Alzheimer disease (AD), but
the mechanisms of interaction, and potential locations, are little understood. This study …

In the present study we performed an integrated proteomics, interactomics and
metabolomics analysis of Longissimus dorsi tender and tough meat samples from Chianina …

Sorting nexins anchor trafficking machines to membranes by binding phospholipids. The
paradigm of the superfamily is sorting nexin 3 (SNX3), which localizes to early endosomes …

Pressure-overload stress to the heart causes pathological cardiac hypertrophy, which
increases the risk of cardiac morbidity and mortality. However, the detailed signaling …